G R Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Sci Rep. 2013;3:1909. doi: 10.1038/srep01909.
Optical transmission through complex media such as biological tissue is fundamentally limited by multiple light scattering. Precise control of the optical wavefield potentially holds the key to advancing a broad range of light-based techniques and applications for imaging or optical delivery. We present a simple and robust digital optical phase conjugation (DOPC) implementation for suppressing multiple light scattering. Utilizing wavefront shaping via a spatial light modulator (SLM), we demonstrate its turbidity-suppression capability by reconstructing the image of a complex two-dimensional wide-field target through a highly scattering medium. Employing an interferometer with a Sagnac-like ring design, we successfully overcome the challenging alignment and wavefront-matching constraints in DOPC, reflecting the requirement that the forward- and reverse-propagation paths through the turbid medium be identical. By measuring the output response to digital distortion of the SLM write pattern, we validate the sub-wavelength sensitivity of the system.
光在复杂介质（如生物组织）中的传输受到多重光散射的根本限制。精确控制光场有望成为推进一系列基于光的成像或光学传输技术和应用的关键。我们提出了一种简单而强大的数字光学相位共轭（DOPC）方法来抑制多重光散射。我们利用空间光调制器（SLM）进行波前整形，通过高度散射介质重建复杂二维广角目标的图像，展示了其消光能力。采用具有萨格纳克环设计的干涉仪，我们成功克服了 DOPC 中具有挑战性的对准和波前匹配约束，反映了前向和反向传播路径通过混浊介质必须相同的要求。通过测量 SLM 写入图案的数字失真的输出响应，我们验证了系统的亚波长灵敏度。
