适体功能化水凝胶光栅用于检测人凝血酶。
Aptamer-functionalized hydrogel diffraction gratings for the human thrombin detection.
机构信息
Department of Chemical Engineering, Laboratory of Advanced Materials (MOE), Tsinghua University, Beijing, PR China.
出版信息
Chem Commun (Camb). 2013 Jul 7;49(53):5957-9. doi: 10.1039/c3cc41827h.
PMID:23715375
Abstract
The aptamer-functionalized hydrogel diffraction gratings were successfully fabricated by incorporating an aptamer and its complementary sequence as crosslinking junctions in the network structure. The gratings showed a sensitive response to human thrombin as read out from the diffracted light.
摘要
适体功能化水凝胶光栅通过将适体及其互补序列作为交联连接点纳入网络结构中成功制备。光栅对人凝血酶表现出敏感的响应，可通过衍射光读出。
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