Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, Tennis Court Road, Cambridge CB2 1QN, UK.
Development. 2013 Jun;140(12):2446-8. doi: 10.1242/dev.097899.
It is relatively unusual for the Nobel Prize in Physiology or Medicine to be made, to a large extent, on the basis of a single author paper, published over 50 years ago, for work carried out by a graduate student. This was largely true of a paper published in 1962 in the journal Development (called at that time the Journal of Embryology and Experimental Morphology). The main subject of that paper was the production of normal tadpoles from the nuclei of intestinal epithelium cells of Xenopus laevis. In view of this unusual situation, I have been invited to comment on the 1962 paper.
将生理学或医学诺贝尔奖在很大程度上基于一篇发表于 50 多年前、由一名研究生完成的单一作者论文授予，这种情况相对少见。这在很大程度上适用于 1962 年发表在《发育》杂志（当时称为《胚胎学与实验形态学杂志》）上的一篇论文。该论文的主要主题是从非洲爪蟾的肠上皮细胞核中产生正常的蝌蚪。鉴于这种不寻常的情况，我应邀对 1962 年的论文进行评论。
