Gebert Anna Felicitas, Schulz Matthias, Haberl Hannes, Thomale Ulrich-Wilhelm
Pediatric Neurosurgery, Campus Virchow Klinikum, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.
Childs Nerv Syst. 2013 Nov;29(11):2019-25. doi: 10.1007/s00381-013-2160-2. Epub 2013 May 29.
Debatable disadvantages of preset differential pressure valves in treating pediatric hydrocephalus are the inability to treat over- and underdrainage after implantation without further surgery. This survey aims to retrospectively determine whether adjustments were performed and effectively used for the individual adaptation of CSF drainage from the shunted patients' and families' perspective.
In a series of 132 consecutive patients (59girls; 73boys, 0-29 years), families, caretakers, or the patients themselves were interviewed about their experiences after using the proGAV (Miethke-Aesculap, Germany) within a CSF-diverting shunt system. Thereby, the necessity and amounts of adjustments were evaluated. The subjective experiences of the adjustment process as well as the subsequent surgical interventions were documented with a follow-up period of 25.6 ± 9 months.
In 87.9 % of the cases, clinical symptoms improved subjectively after valve implantation. A total of 103 adjustments in 69 patients were performed. In 30 % of patients, more than one readjustment was done. As subjective experience, the adjustment process was described by 85 % of patients as painless or merely uncomfortable. Symptoms improved in 91 % in connection to a new pressure setting. During the entire follow-up period, 61 % of all patients remained free of surgery.
The recently used adjustable valves provide good clinical results and seem to lead to satisfactory treatment from the perspective of the affected patients or caretakers. Although a mechanical manipulation of the skin is necessary, the mechanism of the integrated adjustment unit was mostly well tolerated and allows for a noninvasive and MRI stable treatment of over- and underdrainage.
预置压差阀在治疗小儿脑积水方面存在争议性的缺点,即植入后若不进行进一步手术,无法处理引流过多和过少的情况。本调查旨在从分流患者及其家属的角度,回顾性地确定是否进行了调整以及这些调整是否有效地用于脑脊液引流的个体化适配。
在连续的132例患者(59名女孩;73名男孩,年龄0 - 29岁)中,就其在脑脊液分流系统中使用proGAV(德国迈特克 - 蛇牌)后的经历,对家属、护理人员或患者本人进行了访谈。由此评估调整的必要性和调整量。记录调整过程的主观体验以及后续的手术干预情况,随访期为25.6±9个月。
在87.9%的病例中,瓣膜植入后临床症状主观上有所改善。69例患者共进行了103次调整。30%的患者进行了不止一次的重新调整。作为主观体验,85%的患者将调整过程描述为无痛或只是略有不适。91%的患者在设置新压力后症状有所改善。在整个随访期间,61%的患者无需接受手术。
最近使用的可调式瓣膜临床效果良好,从受影响患者或护理人员的角度来看,似乎能带来令人满意的治疗效果。尽管对皮肤进行机械操作是必要的,但集成调整单元的机制大多耐受性良好,且能对引流过多和过少的情况进行无创且磁共振成像(MRI)稳定的治疗。