Verma Rajesh, Kori Prakash, Patil Tushar B, Praharaj Heramba Narayan
Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, India.
BMJ Case Rep. 2013 May 27;2013:bcr2013009090. doi: 10.1136/bcr-2013-009090.
Vitamin B12 deficiency has a wide spectrum of clinical presentation with a variety of neurological symptoms and signs. As a result, many patients lack classic features of advanced severe deficiency. Early diagnosis and treatment are crucial in order to prevent the irreversible damage to the nervous system. We describe a 25-year-old man, who presented with predominant sensory symptoms without any signs on clinical evaluation. His serum vitamin B12 levels were low and neuroimaging revealed myelopathy. The patient was treated promptly with cyanocobalamin injections, which lead to a rapid resolution of symptoms and radiological abnormalities.
维生素B12缺乏具有广泛的临床表现,伴有多种神经症状和体征。因此,许多患者缺乏晚期严重缺乏的典型特征。早期诊断和治疗对于预防神经系统的不可逆损伤至关重要。我们描述了一名25岁男性,他以主要的感觉症状就诊,临床评估未发现任何体征。他的血清维生素B12水平较低,神经影像学显示存在脊髓病。患者立即接受了氰钴胺注射治疗,症状和影像学异常迅速得到缓解。