• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

暴露于广泛的环境毒物与儿童认知发育和行为问题。

Exposure to widespread environmental toxicants and children's cognitive development and behavioral problems.

机构信息

Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Łódź, Poland.

出版信息

Int J Occup Med Environ Health. 2013 Apr;26(2):185-204. doi: 10.2478/s13382-013-0099-x. Epub 2013 May 28.

DOI:10.2478/s13382-013-0099-x
PMID:23715930
Abstract

Nowadays a special attention is focused on prenatal and childhood exposures to a variety of contaminants in the environment, especially toxicants widely present in the environment and their impact on children's health and neurodevelopment. This article aims at evaluating the impact of exposure to several widespread toxicants including: polycyclic aromatic hydrocarbons (PAHs), phthalates, bisphenol A, brominated flame retardants and gas cooking on children's cognitive development and behavioral problems by reviewing most recent published literature. Epidemiological studies focusing on exposure to widespread toxicants and children's development for the last eleven years were identified by a search of the PubMed, Medline, Ebsco and Toxnet literature bases. The combination of following key words was used: 1) referring to the exposure: pregnancy, prenatal exposure, postnatal exposure, gas cooking, exposure to phthalates, bisphenol A, brominated flame retardants, PAHs and 2) referring to outcome: neurodevelopment, neurobehavior, psychomotor development, behavioral problems, cognitive development, mental health, school achievements, learning abilities. The results from the presented studies suggest that there are strong and rather consistent indications that the developing nervous system is particularly vulnerable to insult from low levels of exposure to widespread environmental contaminants such as: phthalates, bisphenol A, brominated flame retardants, polycyclic aromatic hydrocarbons, gas cooking. Considering the suggested health effects, more epidemiologic data is urgently needed and, in the meantime, precautionary policies must be implemented.

摘要

如今,人们特别关注产前和儿童时期暴露于环境中的各种污染物,尤其是广泛存在于环境中的有毒物质及其对儿童健康和神经发育的影响。本文旨在通过回顾最新发表的文献,评估接触多种广泛存在的有毒物质(包括多环芳烃、邻苯二甲酸酯、双酚 A、溴化阻燃剂和燃气烹饪)对儿童认知发展和行为问题的影响。通过在 PubMed、Medline、Ebsco 和 Toxnet 文献数据库中搜索,确定了过去十一年中关注广泛存在的有毒物质暴露与儿童发育的流行病学研究。使用了以下关键词的组合:1)关于暴露:妊娠、产前暴露、产后暴露、燃气烹饪、邻苯二甲酸酯暴露、双酚 A、溴化阻燃剂、多环芳烃和 2)关于结果:神经发育、神经行为、精神运动发育、行为问题、认知发展、心理健康、学业成绩、学习能力。呈现的研究结果表明,有强有力且相当一致的证据表明,发育中的神经系统特别容易受到广泛环境污染物(如邻苯二甲酸酯、双酚 A、溴化阻燃剂、多环芳烃、燃气烹饪)低水平暴露的伤害。考虑到所建议的健康影响,迫切需要更多的流行病学数据,同时必须实施预防政策。

相似文献

1
Exposure to widespread environmental toxicants and children's cognitive development and behavioral problems.暴露于广泛的环境毒物与儿童认知发育和行为问题。
Int J Occup Med Environ Health. 2013 Apr;26(2):185-204. doi: 10.2478/s13382-013-0099-x. Epub 2013 May 28.
2
Prenatal and childhood polybrominated diphenyl ether (PBDE) exposure and attention and executive function at 9-12 years of age.产前及儿童期多溴二苯醚(PBDE)暴露与9至12岁儿童的注意力及执行功能
Neurotoxicol Teratol. 2015 Nov-Dec;52(Pt B):151-61. doi: 10.1016/j.ntt.2015.08.001. Epub 2015 Aug 10.
3
Effects of pre and postnatal exposure to low levels of polybromodiphenyl ethers on neurodevelopment and thyroid hormone levels at 4 years of age.出生前后暴露于低水平多溴二苯醚对 4 岁儿童神经发育和甲状腺激素水平的影响。
Environ Int. 2011 Apr;37(3):605-11. doi: 10.1016/j.envint.2010.12.005. Epub 2011 Jan 14.
4
Epidemiologic evidence of relationships between reproductive and child health outcomes and environmental chemical contaminants.生殖与儿童健康结果和环境化学污染物之间关系的流行病学证据。
J Toxicol Environ Health B Crit Rev. 2008 May;11(5-6):373-517. doi: 10.1080/10937400801921320.
5
Developmental neurotoxicity of persistent organic pollutants: an update on childhood outcome.持久性有机污染物的发育神经毒性:儿童期结局的最新情况
Arch Toxicol. 2015 May;89(5):687-709. doi: 10.1007/s00204-015-1463-3. Epub 2015 Jan 25.
6
Exposure to environmental toxicants and young children's cognitive and social development.暴露于环境毒物与幼儿认知和社会发展。
Rev Environ Health. 2019 Mar 26;34(1):35-56. doi: 10.1515/reveh-2018-0045.
7
Prenatal exposure to organohalogens, including brominated flame retardants, influences motor, cognitive, and behavioral performance at school age.孕期暴露于有机卤化物,包括溴化阻燃剂,会影响学龄期儿童的运动、认知和行为表现。
Environ Health Perspect. 2009 Dec;117(12):1953-8. doi: 10.1289/ehp.0901015. Epub 2009 Aug 31.
8
Human exposure to PBDE and critical evaluation of health hazards.人类接触多溴二苯醚及健康危害的关键评估。
Arch Toxicol. 2015 Mar;89(3):335-56. doi: 10.1007/s00204-015-1457-1. Epub 2015 Jan 31.
9
Exposure to environmental and lifestyle factors and attention-deficit / hyperactivity disorder in children - a review of epidemiological studies.儿童暴露于环境和生活方式因素与注意力缺陷/多动障碍:流行病学研究综述。
Int J Occup Med Environ Health. 2012 Sep;25(4):330-55. doi: 10.2478/S13382-012-0048-0. Epub 2012 Oct 19.
10
Exposure to phthalates: reproductive outcome and children health. A review of epidemiological studies.邻苯二甲酸酯暴露:生殖结局与儿童健康。流行病学研究综述。
Int J Occup Med Environ Health. 2011 Jun;24(2):115-41. doi: 10.2478/s13382-011-0022-2. Epub 2011 May 19.

引用本文的文献

1
Plasma phthalate levels in children with speech delay.语言发育迟缓儿童的血浆邻苯二甲酸盐水平
Toxicol Rep. 2025 May 14;14:102052. doi: 10.1016/j.toxrep.2025.102052. eCollection 2025 Jun.
2
Cognitive Performance and Exposure to Organophosphate Flame Retardants in Children: Evidence from a Cross-Sectional Analysis of Two European Mother-Child Cohorts.儿童的认知能力与有机磷酸酯阻燃剂暴露:来自两个欧洲母婴队列横断面分析的证据
Toxics. 2023 Oct 24;11(11):878. doi: 10.3390/toxics11110878.
3
Rationale for a Multi-Factorial Approach for the Reversal of Cognitive Decline in Alzheimer's Disease and MCI: A Review.
多因素方法逆转阿尔茨海默病和 MCI 认知衰退的理由:综述。
Int J Mol Sci. 2023 Jan 14;24(2):1659. doi: 10.3390/ijms24021659.
4
A Review of Recent Studies on Bisphenol A and Phthalate Exposures and Child Neurodevelopment.双酚A和邻苯二甲酸酯暴露与儿童神经发育的近期研究综述
Int J Environ Res Public Health. 2021 Mar 30;18(7):3585. doi: 10.3390/ijerph18073585.
5
A Meta-Analysis of Stressors from the Total Environment Associated with Children's General Cognitive Ability.环境应激源与儿童一般认知能力关系的汇总分析
Int J Environ Res Public Health. 2020 Jul 29;17(15):5451. doi: 10.3390/ijerph17155451.
6
[Toxicity of dibutyl phthalate in primary cultured rat hippocampal neurons and the toxicological mechanism].邻苯二甲酸二丁酯对原代培养大鼠海马神经元的毒性及毒理学机制
Nan Fang Yi Ke Da Xue Xue Bao. 2020 Feb 29;40(2):225-232. doi: 10.12122/j.issn.1673-4254.2020.02.14.
7
Cognitive function among schoolchildren in Lebanon: association with maternal alcohol drinking and smoking during pregnancy and domestic use of detergents and pesticides during childhood.黎巴嫩学童的认知功能:与孕期母亲饮酒和吸烟以及儿童期家庭使用清洁剂和杀虫剂有关。
Environ Sci Pollut Res Int. 2019 May;26(14):14373-14381. doi: 10.1007/s11356-019-04797-9. Epub 2019 Mar 13.
8
Prenatal exposure to bisphenol A and phthalates and behavioral problems in children at preschool age: the Hokkaido Study on Environment and Children's Health.产前暴露于双酚 A 和邻苯二甲酸酯与学龄前儿童行为问题的关系:北海道环境与儿童健康研究。
Environ Health Prev Med. 2018 Sep 7;23(1):43. doi: 10.1186/s12199-018-0732-1.
9
Prenatal exposure to environmental pollutants and child development trajectories through 7 years.产前暴露于环境污染物与儿童 7 年发育轨迹。
Int J Hyg Environ Health. 2018 May;221(4):616-622. doi: 10.1016/j.ijheh.2018.04.004. Epub 2018 Apr 22.
10
Sex-Specific Effects of Combined Exposure to Chemical and Non-chemical Stressors on Neuroendocrine Development: a Review of Recent Findings and Putative Mechanisms.化学和非化学应激源联合暴露对神经内分泌发育的性别特异性影响:近期研究结果及推测机制综述。
Curr Environ Health Rep. 2017 Dec;4(4):415-425. doi: 10.1007/s40572-017-0165-9.