Tronnier Michael, Semkova Kristina, Wollina Uwe, Tchernev Georgi
Department of Dermatology and Venereology, Hildesheim GmbH, Germany.
Wien Med Wochenschr. 2013 Aug;163(15-16):354-8. doi: 10.1007/s10354-013-0207-3. Epub 2013 May 29.
In faired skinned population the incidence of melanoma is rapidly increasing. Beside environmental factors (UV-exposure) certainly other reasons for the observed "melanoma epidemic" have to be discussed. For diagnostic procedure classical histopathology is accompanied by immunohistochemistry and more recently molecular techniques. For therapy new modalities are available which-after many years of frustrating search for new drugs-are now able to prolong both disease/progression free and overall survival.
在白种人群中，黑色素瘤的发病率正在迅速上升。除了环境因素（紫外线暴露）之外，当然还必须探讨导致观察到的“黑色素瘤流行”的其他原因。对于诊断程序，经典组织病理学辅以免疫组织化学，最近又有了分子技术。对于治疗，有了新的治疗方式，在经过多年令人沮丧的新药研发之后，现在能够延长无疾病进展生存期和总生存期。
