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胃旁路手术后酒精依赖住院人数增加,与限制型减重手术相比。

Increased admission for alcohol dependence after gastric bypass surgery compared with restrictive bariatric surgery.

机构信息

Department of MolecularMedicine and Surgery, Danderyd Hospital.

出版信息

JAMA Surg. 2013 Apr;148(4):374-7. doi: 10.1001/jamasurg.2013.700.

DOI:10.1001/jamasurg.2013.700
PMID:23716012
Abstract

IMPORTANCE

We demonstrate that patients who have undergone gastric bypass surgery (GBS) have a higher risk of inpatient care for alcohol dependence than those who have undergone restrictive surgery. This highlights a need for health care providers to be aware of this so that early detection and treatment can be put in place.

OBJECTIVE

To evaluate inpatient care for alcohol abuse before and after GBS compared with restrictive surgery (vertical banded gastroplasty and gastric banding).

DESIGN

Retrospective population-based cohort study including all patients who underwent GBS, vertical banded gastroplasty, and gastric banding in Sweden from 1980 through 2006. The relative risk of inpatient care for alcohol abuse was studied before and after surgery.

SETTING

All hospitals in Sweden performing bariatric surgery.

PARTICIPANTS

A total of 11,115 patients older than 18 years (mean [SD] age, 40.0 [10.3] years; 77% women) who underwent a primary gastric bypass procedure, vertical banded gastroplasty, and gastric banding during the study period.

MAIN OUTCOME MEASURES

Inpatient care for alcohol abuse, substance abuse, depression, and attempted suicide. RESULTS Mean follow-up time was 8.6 years. Before surgery, there was no difference in inpatient treatment of alcohol abuse among patients who underwent gastric bypass or a restrictive procedure (incidence rate ratio, 1.1; 95% CI, 0.8-1.4). After surgery, there was a 2-fold increased risk of inpatient care for alcohol abuse among patients who had GBS compared with those who had restrictive surgery (hazard ratio, 2.3; 95% CI, 1.7-3.2).

CONCLUSIONS AND RELEVANCE

Patients who had undergone GBS had more than double the risk of inpatient care for alcohol abuse postoperatively compared with patients undergoing a restrictive procedure, highlighting a need for healthcare professionals to be aware of this for early detection and treatment.

摘要

重要性

我们证明,接受胃旁路手术(GBS)的患者比接受限制性手术的患者因酒精依赖住院的风险更高。这凸显了医疗保健提供者需要意识到这一点,以便及早发现和治疗。

目的

评估与限制性手术(垂直带胃成形术和胃带术)相比,GBS 前后患者因酒精滥用而住院的情况。

设计

回顾性基于人群的队列研究,包括 1980 年至 2006 年期间在瑞典接受 GBS、垂直带胃成形术和胃带术的所有患者。研究了手术前后因酒精滥用住院的相对风险。

地点

在瑞典进行减肥手术的所有医院。

参与者

共有 11115 名年龄大于 18 岁的患者(平均[标准差]年龄 40.0[10.3]岁;77%为女性),在研究期间接受了主要胃旁路手术、垂直带胃成形术和胃带术。

主要结局测量

酒精滥用、药物滥用、抑郁和自杀未遂的住院治疗。结果:平均随访时间为 8.6 年。手术前,接受胃旁路手术或限制性手术的患者因酒精滥用而住院治疗没有差异(发病率比,1.1;95%CI,0.8-1.4)。手术后,与接受限制性手术的患者相比,接受 GBS 的患者因酒精滥用而住院的风险增加了 2 倍(风险比,2.3;95%CI,1.7-3.2)。

结论和相关性

与接受限制性手术的患者相比,接受 GBS 的患者术后因酒精滥用住院的风险增加了一倍以上,这凸显了医疗保健专业人员需要对此加以认识,以便及早发现和治疗。

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