Jang Woo Sun, Son In Pyeong, Yeo In Kwon, Park Kui Young, Li Kapsok, Kim Beom Joon, Seo Seong Jun, Kim Myeung Nam, Hong Chang Kwun
Department of Dermatology, College of Medicine, Chung-Ang University, Seoul, Korea.
Ann Dermatol. 2013 May;25(2):181-8. doi: 10.5021/ad.2013.25.2.181. Epub 2013 May 10.
Androgenetic alopecia (AGA) is characterized by the local and gradual transformation of terminal scalp hair into vellus hair, which has a shorter and thinner shaft. There are no studies that analyze annual changes in age, patterns, family history, and associated disease.
We investigated the severity of hair loss, age of onset, the frequency of family history, and past medical histories in Korean patients with AGA.
A retrospective chart review was performed to identify all patients with AGA referred to the Dermatology Clinic at Chung-Ang University Hospital from January 2006 to December 2010.
The age of onset was also gradually decreased from 34.1±10.1 years to 31.6±10.9 years between 2006 and 2010. In female patients, specific annual changes were not observed. Hamilton-Norwood Type IIIv AGA was most common in male patients and Ludwig Type I AGA was most common in female patients at all times between 2006 and 2010. The majority of patients with AGA had a family history of baldness and was most commonly associated with a paternal pattern of inheritance. Seborrheic dermatitis was the most common associated disease in male and female patients.
Our results show the possibilities that the average age of onset is decreasing. The period of the present study was only 5 years, which is not sufficient for the precise determination of onset age for AGA. Clearly, a long-term study is needed.
雄激素性脱发（AGA）的特征是头皮终毛局部逐渐转变为毳毛，后者的毛干更短更细。目前尚无研究分析年龄、脱发模式、家族史及相关疾病的年度变化情况。
我们调查了韩国AGA患者的脱发严重程度、发病年龄、家族史频率及既往病史。
通过回顾性病历审查，确定2006年1月至2010年12月期间转诊至中央大学医院皮肤科门诊的所有AGA患者。
2006年至2010年期间，发病年龄也从34.1±10.1岁逐渐降至31.6±10.9岁。女性患者未观察到特定的年度变化。2006年至2010年期间的所有时间里，Hamilton-Norwood IIIv型AGA在男性患者中最为常见，Ludwig I型AGA在女性患者中最为常见。大多数AGA患者有秃发家族史，且最常见的是父系遗传模式。脂溢性皮炎是男性和女性患者中最常见的相关疾病。
我们的结果显示了发病平均年龄可能正在降低的可能性。本研究的时间仅为5年，不足以精确确定AGA的发病年龄。显然，需要进行长期研究。
