Baghestani Shahram, Moosavi Abdullah, Eftekhari Tasnim
Department of Dermatology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Ann Dermatol. 2013 May;25(2):223-5. doi: 10.5021/ad.2013.25.2.223. Epub 2013 May 10.
Lichen planus and vitiligo are common skin disorders. Colocalization which is rarely reported may consider the koebner phenomenon related to the photo damage causing initiation of lichen planus over vitiliginous skin. We report a 37-year-old mother and her 23-year-old daughter, both farmers and known cases of vitiligo with subsequent gradual onset of pruritic skin lesions of lichen planus starting first over previous vitiliginous skin on sun exposed areas. Coexistence and colocalization of lichen planus and vitiligo in two members of a family is very rare and has not been reported previously according to our knowledge. Predominant colocalization was on vitiliginous areas which may explain actinic damage as a triggering factor for inducing lichen planus in long-standing vitiligo and supports its pathogenic relationship.
扁平苔藓和白癜风是常见的皮肤疾病。很少有报道的共定位现象可能与同形反应有关，这种同形反应与光损伤有关，可导致白癜风皮肤引发扁平苔藓。我们报告了一位37岁的母亲和她23岁的女儿，她们都是农民，均为白癜风患者，随后逐渐出现瘙痒性扁平苔藓皮肤损害，首先出现在暴露于阳光下的先前白癜风皮肤上。扁平苔藓和白癜风在一个家庭的两名成员中共存和共定位非常罕见，据我们所知，此前尚未有过报道。主要共定位发生在白癜风区域，这可能解释了光化损伤是长期白癜风中诱发扁平苔藓的触发因素，并支持了它们之间的致病关系。
