Rodríguez Miguel Angel Palomero, Mencía Teresa Pérez, Alvarez Felipe Villar, Báez Yolanda Laporta, Pérez Gloria María Santos, García Andrés López
Department of Anesthesiology, Hospital de Madrid, Madrid, Spain.
Saudi J Anaesth. 2013 Jan;7(1):90-2. doi: 10.4103/1658-354X.109836.
Myasthenia gravis (MG) is an autoimmune disease with an incidence of 2-10/100,000 cases per year, characterized by muscle weakness secondary to destruction of postsynaptic acetylcholine receptors. In these patients, important perioperative issues remain unresolved, namely, optimal administration of cholinesterase inhibitors, risks of regional anesthesia, and prediction of need of postoperative mechanical ventilation. We describe the use of a low-dose spinal anesthesia in a patient with MG who was submitted for emergence exploratory laparotomy. The utilization of low-dose spinal anesthesia allowed us to perform surgery with no adverse respiratory or cardiovascular events in this patient.
重症肌无力（MG）是一种自身免疫性疾病，年发病率为2 - 10/100,000例，其特征是突触后乙酰胆碱受体破坏继发肌肉无力。对于这些患者，重要的围手术期问题仍未得到解决，即胆碱酯酶抑制剂的最佳给药、区域麻醉的风险以及术后机械通气需求的预测。我们描述了在一名因急诊剖腹探查术而接受治疗的MG患者中使用低剂量脊髓麻醉的情况。低剂量脊髓麻醉的应用使我们能够在该患者身上进行手术，且未发生不良呼吸或心血管事件。
