Stevens R D
Department of Anesthesia and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA.
Curr Opin Anaesthesiol. 2001 Dec;14(6):693-8. doi: 10.1097/00001503-200112000-00016.
The neuromuscular disorders are associated with diminished cardiopulmonary reserves, deficient airway protection mechanisms, and atypical responses to drugs used during anesthesia. Many of these conditions are uncommon, and methodologically sound evidence to guide clinical practice is limited. The disorders discussed in the present review are the motor neuron diseases, peripheral neuropathies, myasthenic syndromes, and myopathies, including malignant hyperthermia. Recent data on pathogenesis and medical management are outlined, as are studies relating to anesthesia and the perioperative period.
神经肌肉疾病与心肺储备功能降低、气道保护机制不足以及麻醉期间使用的药物的非典型反应有关。这些病症中的许多都不常见，指导临床实践的方法学上可靠的证据有限。本综述中讨论的疾病包括运动神经元疾病、周围神经病、肌无力综合征和肌病，其中包括恶性高热。概述了有关发病机制和药物治疗的最新数据，以及与麻醉和围手术期相关的研究。
