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刚果民主共和国卢本巴希省医院杰森·森德韦重症监护病房破伤风患者的预后情况

Prognosis of tetanus patients in the intensive care unit of Provincial Hospital Jason Sendwe, Lubumbashi, DR Congo.

作者信息

Muteya Michel Manika, Kabey Alain Kabey a, Lubanga Théophile Muyumba, Tshamba Henri Mundongo, Nkoy Albert Mwembo Tambwe a

机构信息

Department of Anesthesiology-Intensive Care, Cliniques Universitaires de Lubumbashi, University of Lubumbashi, B P 1825, DR Congo.

出版信息

Pan Afr Med J. 2013 Mar 10;14:93. doi: 10.11604/pamj.2013.14.93.2180. Print 2013.

Abstract

Tetanus is still a public health problem in developing countries including the Democratic Republic of Congo. The objective of this study was to determine the prognosis of patients with tetanus admitted in the Intensive Care Unit (ICU) of Provincial Hospital Jason Sendwe, Lubumbashi, DR Congo. This is a descriptive study which collected information from registers and medical records of patients admitted for tetanus in the ICU of Jason Sendwe Hospital, between January 2005 and December 2009. We calculated the parameters of position, dispersion as well as frequencies. We used the test of independent association of prognosis (death versus survival). Tetanus constituted 2.1% of admissions in the ICU during the 5-year period. The average age of patients was 39.38 ± 17; majority of patients were males (95.5%). The majority of patients lived the townships of Kampemba (27.3%), Kenya (22.7%), and Annexe (18.2%). All patients presented the generalized form of the infection. The door of entry was detectable in 71.5% of cases, localized mainly to the lower limbs (61.9%). The average length of stay was 11.29 ± 11.39 days. Mortality was observed in 52.4% of cases. This mortality was statistically significant in patients aged more than 40 years (p=0.029) but not not related to the length of stay (p=0.080) nor the location of point of entry(p=0.28). In our environment the prognosis of tetanus remains severe. This disease is still frequent in the city of Lubumbashi; sensibilisation of population on preventive strategies as well as setting up appropriate structures for better management of cases is required.

摘要

破伤风在包括刚果民主共和国在内的发展中国家仍是一个公共卫生问题。本研究的目的是确定刚果民主共和国卢本巴希市杰森·森德韦省立医院重症监护病房(ICU)收治的破伤风患者的预后情况。这是一项描述性研究,收集了2005年1月至2009年12月期间在杰森·森德韦医院ICU因破伤风入院患者的登记信息和病历。我们计算了位置、离散参数以及频率。我们使用了预后独立关联检验(死亡与存活)。在这5年期间,破伤风占ICU入院病例的2.1%。患者的平均年龄为39.38±17岁;大多数患者为男性(95.5%)。大多数患者居住在坎彭巴(27.3%)、肯尼亚(22.7%)和附属区(18.2%)等城镇。所有患者均表现为感染的全身形式。71.5%的病例可检测到感染入口,主要集中在下肢(61.9%)。平均住院时间为11.29±11.39天。52.4%的病例观察到死亡。40岁以上患者的死亡率具有统计学意义(p = 0.029),但与住院时间(p = 0.080)和感染入口位置(p = 0.28)无关。在我们所处的环境中,破伤风的预后仍然很严峻。这种疾病在卢本巴希市仍然很常见;需要提高民众对预防策略的认识,并建立适当的机构以更好地管理病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9332/3664872/2cf528d7494a/PAMJ-14-93-g001.jpg

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