Jules Stein Eye Institute, Neuro-Ophthalmology Division, University of California, Los Angeles, Los Angeles, California, USA.
J Neuroophthalmol. 2013 Sep;33(3):232-4. doi: 10.1097/WNO.0b013e31828eecbd.
To evaluate the obstructive sleep apnea syndrome (OSAS) in patients with nonarteritic anterior ischemic optic neuropathy (NAION).
We recruited 27 patients with NAION and 27 age-matched and sex-matched controls who also were similar for systemic risk factors such as diabetes mellitus, hypertension, and hypercholesterolemia. All patients and controls underwent overnight polysomnography for the diagnosis of OSAS and calculation of apnea-hypopnea index (AHI).
Patients and controls were statistically similar in terms of age, sex, gender, smoking, systemic risk factors, neck circumference, and body mass index. The subjects with AHI ≥ 20 were accepted as OSAS. Fifteen of 27 patients (55.6%) with NAION and 6 of 27 controls (22.2%) had OSAS (P < 0.05).
The prevalence of OSAS was higher in patients with NAION, and the difference between patient and control groups was statistically significant (P < 0.05). This result supports prior series suggesting the association between NAION and OSAS.
评估非动脉炎性前部缺血性视神经病变（NAION）患者的阻塞性睡眠呼吸暂停综合征（OSAS）。
我们招募了 27 名 NAION 患者和 27 名年龄和性别匹配的对照组患者，这些患者在糖尿病、高血压和高胆固醇血症等系统性危险因素方面也相似。所有患者和对照组均接受了整夜多导睡眠图检查，以诊断 OSAS 并计算呼吸暂停低通气指数（AHI）。
患者和对照组在年龄、性别、性别、吸烟、系统性危险因素、颈围和体重指数方面具有统计学上的相似性。AHI≥20 的患者被认为患有 OSAS。27 名 NAION 患者中有 15 名（55.6%）和 27 名对照组中有 6 名（22.2%）患有 OSAS（P<0.05）。
NAION 患者中 OSAS 的患病率较高，患者组和对照组之间的差异具有统计学意义（P<0.05）。这一结果支持了先前的研究结果，即 NAION 与 OSAS 之间存在关联。
