Royal Alexandra Hospital, UK.
Scott Med J. 2013 Aug;58(3):134-8. doi: 10.1177/0036933013490381. Epub 2013 May 29.
Alcoholic liver disease including cirrhosis is a major health burden with huge cost to the National Health Service due to frequent hospital admissions of patients with alcoholic liver disease. The highest morbidity and mortality from alcoholic liver disease in Western Europe is in the West of Scotland. This study analyses the mortality and re-admission rates of patients admitted with alcoholic liver disease to a Glasgow hospital and compares the outcome with a Scotland wide historic control. Mortality in the study of 124 patients admitted to the hospital with alcoholic liver disease was 18% during index admission, and was 40% when including follow-up of one year after discharge. Re-admissions were high in this population. Seventy-five per cent of patients had at least one re-admission within one year, and patients spent an average of over one month in hospital during the study period. Survival rates in the Glasgow hospital were comparable to survival in the Scottish cohort. However, re-admission rates were significantly higher in the Glasgow hospital. In conclusion, patients with alcoholic liver disease requiring hospitalisation have very high mortality and frequent re-admissions.
酒精性肝病包括肝硬化,是国家卫生服务系统的主要健康负担之一,因为经常有酒精性肝病患者住院。在西欧,酒精性肝病的发病率和死亡率最高的是苏格兰西部。本研究分析了因酒精性肝病住院的患者在格拉斯哥医院的死亡率和再入院率,并与苏格兰历史对照进行了比较。在这项对 124 名因酒精性肝病住院的患者的研究中,住院期间的死亡率为 18%,出院后一年的死亡率为 40%。该人群的再入院率很高。75%的患者在一年内至少有一次再入院,患者在研究期间平均在医院住院超过一个月。格拉斯哥医院的生存率与苏格兰队列的生存率相当。然而,格拉斯哥医院的再入院率明显更高。总之,需要住院治疗的酒精性肝病患者死亡率非常高,且经常再入院。