胆管细胞生理学。
Physiology of cholangiocytes.
机构信息
Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
出版信息
Compr Physiol. 2013 Jan;3(1):541-65. doi: 10.1002/cphy.c120019.
Abstract
Cholangiocytes are epithelial cells that line the intra- and extrahepatic ducts of the biliary tree. The main physiologic function of cholangiocytes is modification of hepatocyte-derived bile, an intricate process regulated by hormones, peptides, nucleotides, neurotransmitters, and other molecules through intracellular signaling pathways and cascades. The mechanisms and regulation of bile modification are reviewed herein.
摘要
胆管细胞是排列在胆道的肝内和肝外导管的上皮细胞。胆管细胞的主要生理功能是修饰由肝细胞产生的胆汁，这是一个通过细胞内信号通路和级联反应由激素、肽、核苷酸、神经递质和其他分子调节的复杂过程。本文综述了胆汁修饰的机制和调节。
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