Milchev N, Pekhlivanov B, Krŭsteva M, Chalŭkova Zh, Stankova G
Akush Ginekol (Sofiia). 1990;29(1):13-6.
The authors investigated cellular and humoral immunity as well as the amount of circulating immune complexes (CIC) in 84 women, 52 of whom were healthy nonpregnant and 32 with normal pregnancy during the first trimester. Considerable changes were established in the immune status-depression of cellular immunity in pregnant women, an increase of the amount of CIC in the same women, humoral immunity did not show synonymous changes a reduction of IgG content in pregnant women and an increase of IgA in the same group. The level of IgM was not altered. The possible causes for the discovered changes are discussed.
作者对84名女性的细胞免疫、体液免疫以及循环免疫复合物（CIC）的含量进行了研究，其中52名是健康未孕女性，32名是孕早期的正常孕妇。研究发现，孕妇的免疫状态发生了显著变化——细胞免疫受到抑制，CIC含量增加，体液免疫未出现相应变化，孕妇体内IgG含量降低，IgA含量增加。IgM水平未改变。文中还讨论了这些发现变化的可能原因。
