Carranza-Lira Sebastián, Camarillo-Quesada Argelia Elisa, Ramos-León Julio César
División de Educación en Salud, Hospital Ginecología y Obstetricia Luis Castelazo Ayala, Instituto Mexicano del Seguro Social, México, DF.
Ginecol Obstet Mex. 2013 Apr;81(4):190-4.
Brachial artery doppler fluxometry permits to evaluate the endothelial function in a non-invasive way.
To know the effect of vasomotor symptoms in brachial artery flux ultrasonographic parameters in Mexican postmenopausal women.
A prospective study was done including postmenopausal women divided into two groups: I) without hot-flushes and II) with hot-flushes. To all them Doppler fluxometry was done. The pulsatility index resistance index and arterial diameter were determined previous and after the hyperemic stimulus. The intensity of vasomotor symptoms (hot-flushes, throbs and sweatings) was determined using an analog visual scale; and the number of each one of them was determined. For statistical analysis Student t test for independent and paired samples was used. Correlation analysis was done between age, time since menopause, hot flushes, throbs and sweating with pulsatility index, resistance index and arterial diameter previous and after hyperemic stimulus.
Thirty patients were divided into two groups of 15 women each. No differences were found between the groups neither in age, anthropometric variables, pulsatility index, resistance index nor arterial diameter neither before nor after hyperemic stimulus; only there was a statistically significant increase in arterial diameter after hyperemic stimulus in group I (p < 0.001). In group I a positive correlation was found between age and baseline resistance index and in group II between baseline resistance index and the number of throbs per week.
Women with hot-flushes have a healthier endothelium.
肱动脉多普勒血流测定法能够以非侵入性方式评估内皮功能。
了解血管舒缩症状对墨西哥绝经后女性肱动脉血流超声参数的影响。
进行了一项前瞻性研究，纳入绝经后女性并分为两组：I）无潮热组和II）有潮热组。对所有受试者进行了多普勒血流测定。在充血刺激前后测定搏动指数、阻力指数和动脉直径。使用视觉模拟量表确定血管舒缩症状（潮热、悸动和出汗）的强度，并确定每种症状的发作次数。统计学分析采用独立样本和配对样本的Student t检验。对年龄、绝经时间、潮热、悸动和出汗与充血刺激前后的搏动指数、阻力指数和动脉直径进行相关性分析。
30名患者分为两组，每组15名女性。两组在年龄、人体测量变量、搏动指数、阻力指数以及充血刺激前后的动脉直径方面均未发现差异；仅在I组中，充血刺激后动脉直径有统计学显著增加（p < 0.001）。在I组中，年龄与基线阻力指数之间存在正相关，在II组中，基线阻力指数与每周悸动次数之间存在正相关。
有潮热症状的女性内皮功能更健康。
