Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busanjin-gu, Busan, South Korea.
World J Surg Oncol. 2013 May 30;11:121. doi: 10.1186/1477-7819-11-121.
No study on ultrasound-guided fine-needle aspiration (US-FNA) for the diagnosis of retrojugular lymph node has been reported. The present study aimed to introduce US-FNA techniques for retrojugular lymph node and to evaluate their efficacy.
Of the 788 patients who underwent US-FNA of the cervical lymph node, 41 patients underwent US-FNAs of retrojugular lymph node and were included in this study. The adequacy and efficacy of US-FNA of retrojugular lymph node and related complications during or after the procedure were assessed.
Of the 41 patients, 35 (85.4%) were adequately diagnosed in cytological analysis; four predominantly cystic lymph nodes were identified. Based on cytohistopathology results, thyroglobulin measurement, tuberculosis polymerase chain reaction, and sonographic follow-up, malignant (n = 26) and benign (n = 15) lymph nodes were confirmed. When six lymph nodes with inadequate cytology were classified as benign and malignant, the sensitivity, specificity, positive and negative predictive values, and accuracy of US-FNA in differentiating malignant from benign lesions were 69.2% and 92.3%, 100% and 100%, 100% and 100%, 65.2% and 88.2%, and 80.5% and 95.1%, respectively. No substantial complications related to the US-FNA procedure were observed.
The present US-FNA method may be helpful for the diagnosis of retrojugular lymph node.
目前尚无关于超声引导下细针抽吸(US-FNA)用于诊断颈后淋巴结的研究。本研究旨在介绍颈后淋巴结 US-FNA 技术,并评估其疗效。
在 788 例行颈部淋巴结 US-FNA 的患者中,41 例行颈后淋巴结 US-FNA 并纳入本研究。评估颈后淋巴结 US-FNA 的充分性和有效性,以及术中或术后相关并发症。
41 例患者中,35 例(85.4%)细胞学分析结果充分;4 例主要为囊性淋巴结。根据细胞组织病理学结果、甲状腺球蛋白测量、结核聚合酶链反应和超声随访,确认恶性(n=26)和良性(n=15)淋巴结。当 6 例细胞学不充分的淋巴结被归类为良性和恶性时,US-FNA 对良恶性病变的鉴别诊断的灵敏度、特异性、阳性和阴性预测值及准确率分别为 69.2%和 92.3%、100%和 100%、100%和 100%、65.2%和 88.2%、80.5%和 95.1%。未观察到与 US-FNA 操作相关的严重并发症。
本研究的 US-FNA 方法可能有助于颈后淋巴结的诊断。