University of Sevilla, C/ Avicena s/n, 41009-Sevilla, Spain,
Med Oral Patol Oral Cir Bucal. 2013 Sep 1;18(5):e773-9. doi: 10.4317/medoral.19148.
The purpose of this study was to investigate the prevalence of apical periodontitis (AP) and endodontic treatment in liver transplant candidates and control healthy subjects.
A descriptive cross-sectional study. Forty two liver transplant candidates (LTC) (study group) and 42 control subjects. Digital panoramic radiographs where used. Periapical status was scored according to the periapical index (PAI). Results were analysed statistically using the Chi-squared test and logistic regression.
Radiographic signs of AP in one or more teeth was found in 79% of patients in the study group and in 50% of control subjects (p = 0.008; OR = 3.7; C. I. 95% = 1.4 - 9.5). One or more root-filled teeth (RFT) were found in 19% and 62% of study and control subjects, respectively (p = 0.0001; OR = 0.14; 95% C. I. = 0.05 - 0.38). Among LTC patients 14.7% of the teeth had AP, whereas in the control subjects 4.2% of teeth were affected (p= 0.0002). The percentage of RFT in the study and control groups was 1.5% and 6.8%, respectively (p = 0.0002).
Liver transplant candidates have significantly higher prevalence of radiographic periapical lesions and lower frequency of RFT than controls healthy subjects.
本研究旨在调查肝移植候选者和健康对照者中根尖周炎（AP）和根管治疗的患病率。
一项描述性的横断面研究。共纳入 42 名肝移植候选者（LTC）（研究组）和 42 名健康对照者。使用数字化全景片。根据根尖指数（PAI）对根尖状态进行评分。使用卡方检验和逻辑回归对结果进行统计学分析。
研究组中 79%的患者和对照组中 50%的患者存在一个或多个牙齿的 AP 放射学征象（p=0.008；OR=3.7；95%CI=1.4-9.5）。研究组和对照组中分别有 19%和 62%的患者存在一个或多个根管充填的牙齿（RFT）（p=0.0001；OR=0.14；95%CI=0.05-0.38）。在 LTC 患者中，14.7%的牙齿有 AP，而在对照组中，4.2%的牙齿受到影响（p=0.0002）。研究组和对照组的 RFT 比例分别为 1.5%和 6.8%（p=0.0002）。
与健康对照组相比，肝移植候选者的放射学根尖病变患病率显著更高，根管治疗的频率更低。
