Facultad de Odontología, Universidad de Sevilla C/ Avicena s/n, 41009-Sevilla, Spain
Med Oral Patol Oral Cir Bucal. 2024 Sep 1;29(5):e711-e718. doi: 10.4317/medoral.26697.
The aim of this systematic review and meta-analysis was to analyze the scientific evidence about the association between osteoporosis in postmenopausal women and the prevalence of apical periodontitis, assessed radiographically.
PRISMA Guidelines have been followed. The research question was: In adult women, does the presence or absence of osteoporosis affect the prevalence of AP, radiographically diagnosed? A systematic search was performed in PubMed/MEDLINE, Web of Science, Scopus and EMBASE. The meta-analyses were calculated with the Open Meta Analyst software. Risk of bias was assessed using the Newcastle Ottawa Scale. The certainty of evidence was assessed by GRADE.
Four studies were selected. Meta-analysis showed an overall OR = 2.2 (95% CI = 0.94 - 4.97; p = 0.07), indicating that osteoporotic women had approximately twice the probability of having periapical lesions, compared to control women, although the difference was only marginally significant. The overall risk of bias of the included studies was moderate, and the certainty of evidence was low.
Apical periodontitis, assessed as periapical lesion, is more frequently diagnosed in osteoporotic women, who are twice as likely to have periapical radiolucent lesions.
本系统评价和荟萃分析的目的是分析关于绝经后妇女骨质疏松症与影像学诊断的根尖周炎患病率之间关联的科学证据。
遵循 PRISMA 指南。研究问题是：在成年女性中，骨质疏松症的存在与否是否会影响影像学诊断的 AP 患病率？在 PubMed/MEDLINE、Web of Science、Scopus 和 EMBASE 中进行了系统搜索。使用 Open Meta Analyst 软件计算荟萃分析。使用纽卡斯尔-渥太华量表评估偏倚风险。使用 GRADE 评估证据确定性。
选择了四项研究。荟萃分析显示总体 OR = 2.2（95%CI = 0.94 - 4.97；p = 0.07），表明与对照组女性相比，骨质疏松症女性发生根尖周病变的可能性大约增加了两倍，尽管差异仅略有统计学意义。纳入研究的总体偏倚风险为中度，证据确定性为低。
骨质疏松症女性更常被诊断为根尖周炎，其发生根尖周透影病变的可能性是对照组女性的两倍。
