Yaman Alper, Ozturk Cengizhan, Huijing Peter A, Yucesoy Can A
Institute of Biomedical Engineering, Boğaziçi University, Istanbul 34342, Turkey.
J Biomech Eng. 2013 Sep;135(9):91003. doi: 10.1115/1.4024573.
Evidence on epimuscular myofascial force transmission (EMFT) was shown for undissected muscle in situ. We hypothesize that global length changes of gastrocnemius muscle-tendon complex in vivo will cause sizable and heterogeneous local strains within all muscles of the human lower leg. Our goal is to test this hypothesis. A method was developed and validated using high-resolution 3D magnetic resonance image sets and Demons nonrigid registration algorithm for performing large deformation analyses. Calculation of strain tensors per voxel in human muscles in vivo allowed quantifying local heterogeneous tissue deformations and volume changes. After hip and knee movement (Δ knee angle ≈ 25 deg) but without any ankle movement, local lengthening within m. gastrocnemius was shown to occur simultaneously with local shortening (maximally by +34.2% and -32.6%, respectively) at different locations. Moreover, similar local strains occur also within other muscles, despite being kept at constant muscle-tendon complex length. This is shown for synergistic m. soleus and deep flexors, as well as for antagonistic anterior crural and peroneal muscle groups: minimum peak lengthening and shortening equaled 23.3% and 25.54%, respectively despite global isometric conditions. These findings confirm our hypothesis and show that in vivo, muscles are in principle not independent mechanically.
已有证据表明，在未解剖的原位肌肉中存在肌外肌筋膜力传递（EMFT）。我们假设，体内腓肠肌肌腱复合体的整体长度变化将在人类小腿的所有肌肉内引起相当大的局部应变且应变不均一。我们的目标是验证这一假设。我们开发并验证了一种方法，该方法使用高分辨率3D磁共振图像集和 demons 非刚性配准算法来进行大变形分析。通过计算体内人体肌肉中每个体素的应变张量，可以量化局部组织变形和体积变化。在髋关节和膝关节运动（膝关节角度变化约25度）但无任何踝关节运动后，腓肠肌内不同位置同时出现局部拉长和局部缩短（最大分别为+34.2%和-32.6%）。此外，尽管肌腱复合体长度保持不变，但其他肌肉内也会出现类似的局部应变。比目鱼肌和深层屈肌等协同肌以及小腿前肌群和腓骨肌群等拮抗肌均是如此：尽管处于整体等长状态，但最小峰值拉长和缩短分别为23.3%和25.54%。这些发现证实了我们的假设，并表明在体内，肌肉原则上在机械方面并非相互独立。
