Ravari Hassan, Modaghegh Mohammad-Hadi Saeed, Kazemzadeh Gholam Hosein, Johari Hamed Ghoddusi, Vatanchi Attieh Mohammadzadeh, Sangaki Abolghasem, Shahrodi Mohammad Vahedian
Vascular and Endovascular Surgery Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
J Cutan Aesthet Surg. 2013 Jan;6(1):17-20. doi: 10.4103/0974-2077.110091.
Vacuum-assisted closure (VAC) is a new method in wound care which speeds wound healing by causing vacuum, improving tissue perfusion and suctioning the exudates. This study aims to evaluate its efficacy in the treatment of diabetic foot ulcers.
Thirteen patients with diabetic foot ulcers were enrolled in the moist dressing group, and 10 patients in the VAC group. The site, size and depth of the wound were inspected and recorded before and every three days during the study period. Patient satisfaction and formation of granulation tissue were also assessed.
Improvement of the wound in the form of reducing the diameter and depth and increasing proliferation of granulation tissue was significant in most of the patients of the VAC group after two weeks. Satisfaction of patients in the VAC group was evaluated as excellent as no amputation was done in this group. Wagner score was reduced in both the study groups, although this decrement was not significant in the moist dressing group.
VAC appears to be as safe as and more efficacious than moist dressing for the treatment of diabetic foot ulcers.
负压封闭引流(VAC)是伤口护理中的一种新方法,通过产生负压、改善组织灌注和抽吸渗出物来加速伤口愈合。本研究旨在评估其治疗糖尿病足溃疡的疗效。
湿润敷料组纳入13例糖尿病足溃疡患者,负压封闭引流组纳入10例患者。在研究期间,于治疗前及每隔三天检查并记录伤口的部位、大小和深度。同时评估患者满意度及肉芽组织形成情况。
两周后,负压封闭引流组大多数患者的伤口在缩小直径、减小深度以及增加肉芽组织增生方面有显著改善。负压封闭引流组患者满意度评估为优秀,因为该组未进行截肢手术。两个研究组的瓦格纳评分均降低,尽管湿润敷料组的降幅不显著。
对于糖尿病足溃疡的治疗,负压封闭引流似乎与湿润敷料一样安全且更有效。