（±）-（4RS，5RS，7SR）-4- [（1RS，2RS，3RS，6RS）-3-苯氧基-2-（2-羟基-乙基）-6-甲氧基甲氧基-2-甲基-环己基] -8,10,10-三甲基-2-氧代-1,3-二氧杂螺[4.5]癸-8-烯-7-基苯甲酸酯苯单溶剂合物的晶体结构

Crystal structure of (±)-(4RS,5RS,7SR)-4-[(1RS,2RS,3RS,6RS)-3-benzo-yloxy-2-(2-hy-droxy-ethyl)-6-meth-oxy-meth-oxy-2-methyl-cyclo-hex-yl]-8,10,10-trimethyl-2-oxo-1,3-dioxa-spiro-[4.5]dec-8-en-7-yl benzoate benzene monosolvate.

作者信息

Oishi Takeshi, Yamaguchi Yuu, Fukaya Keisuke, Sugai Tomoya, Watanabe Ami, Sato Takaaki, Chida Noritaka

机构信息

School of Medicine, Keio University, Hiyoshi 4-1-1, Kohoku-ku, Yokohama 223-8521, Japan.

Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi 3-14-1, Kohoku-ku, Yokohama 223-8522, Japan.

出版信息

Acta Crystallogr E Crystallogr Commun. 2015 Jan 1;71(Pt 1):8-11. doi: 10.1107/S2056989014026048.

In the title compound, C36H44O10·C6H6, the dioxolane ring adopts an envelope conformation with the C atom bonded to the H atom as the flap, while the cyclo-hexene and cyclo-hexane rings are in half-chair and chair conformations, respectively. In the crystal, a pair of O-H⋯O hydrogen bonds with an R 2 (2)(26) graph-set motif connect the benzoate mol-ecules into an inversion dimer. The dimers are linked by a weak C-H⋯O inter-action into a tape structure along [01-1]. The benzene mol-ecule links the tapes through C-H⋯O and C-H⋯π inter-actions, forming a sheet parallel to (100).