Hoxha Syheda Latifi, Ibishi Vlora Ademi, Brovina Ahmet, Hoxha Mynevere, Lulaj Shefqet
Obstetrics and Gynecology Clinic, University Clinical Center of Kosova, Prishtina, 10000, Kosova.
J Med Case Rep. 2013 May 31;7:148. doi: 10.1186/1752-1947-7-148.
Acute leukemia is rare in pregnancy. The importance of promptly diagnosing and treating this disease in pregnancy stems from its life-threatening potential, both to the mother and fetus.
We report a case of relapse of acute myeloid leukemia at 23 weeks of pregnancy in a 24-year-old Albanian woman. Our patient categorically refused chemotherapy treatment, and in her 35th week of gestation, severe hemorrhagic diathesis rapidly developed. The manifestation and course of this life-threatening complication posed therapeutic challenges for the attending medical team.
Based both on our experience and the results of other gynecological studies, there exists a strong indication that the earlier a patient's chemotherapy treatment begins, the better the maternal outcome. We support chemotherapy for patients who are pregnant presenting with such illness. The present case report testifies that refusal of chemotherapy by such patients is a high-risk decision.
急性白血病在孕期较为罕见。孕期及时诊断和治疗这种疾病至关重要，因为它对母亲和胎儿都有潜在的生命威胁。
我们报告一例24岁阿尔巴尼亚女性在孕23周时急性髓系白血病复发的病例。我们的患者坚决拒绝化疗，在妊娠35周时，严重出血素质迅速发展。这种危及生命的并发症的表现和病程给主治医疗团队带来了治疗挑战。
基于我们的经验以及其他妇科研究结果，有强有力的迹象表明，患者化疗开始得越早，母亲的预后越好。我们支持对患有此类疾病的孕妇进行化疗。本病例报告证明，此类患者拒绝化疗是一个高风险的决定。
