Tsouskas L I, Fentiman I S
ICRF Clinical Oncology Unit, Guy's Hospital, London, England.
Breast Cancer Res Treat. 1990 May;15(3):185-90. doi: 10.1007/BF01806355.
As a measure of cosmetic outcome, the compliance of normal and irradiated breasts has been quantified using a new method of Breast Compliance Evaluation (BCE). A total of 151 women were studied, of whom 100 were normal controls and 51 had previous breast irradiation as part of breast-conserving treatment. Compliance was taken as the difference between the anterior breast surface length from infra-mammary fold to the nipple when the patient was in erect and supine positions. Irradiated cases were rated as having satisfactory outcome (good or excellent cosmetic result) or unsatisfactory (fair or poor cosmetic result). Mean compliance of normal cases was 1.8 cm. In the irradiated women with satisfactory cosmetic results, mean compliance was 1.45 compared with only 0.77 cm in those with unsatisfactory outcome. The difference between the compliance of both breasts was 0.1 cm for the controls, 0.3 cm in the satisfactory group and 2 cm in the unsatisfactory group. A difference in compliance greater than 1 cm was usually associated with an unsatisfactory cosmetic outcome. Factors determining cosmetic outcome included volume of excised lump and breast size. The cosmetic result was not affected by tumour site, clinical or pathological tumour size, or the total number of axillary nodes excised. This simple, painless, and easily reproducible measurement may be a useful objective indicator of cosmetic result after conservative treatment of early breast cancer.
作为一种美容效果的衡量指标，采用一种新的乳房顺应性评估（BCE）方法对正常乳房和放疗后乳房的顺应性进行了量化。共研究了151名女性，其中100名是正常对照，51名曾接受过乳房保留治疗中的乳房放疗。顺应性被定义为患者直立位和仰卧位时从乳房下皱襞到乳头的前胸壁表面长度之差。放疗病例被评定为具有满意的结果（良好或优秀的美容效果）或不满意（一般或差的美容效果）。正常病例的平均顺应性为1.8厘米。在美容效果满意的放疗女性中，平均顺应性为1.45厘米，而美容效果不满意者仅为0.77厘米。对照组双侧乳房顺应性之差为0.1厘米，满意组为0.3厘米，不满意组为2厘米。顺应性差异大于1厘米通常与不满意的美容效果相关。决定美容效果的因素包括切除肿块的体积和乳房大小。美容效果不受肿瘤部位、临床或病理肿瘤大小或切除腋窝淋巴结总数的影响。这种简单、无痛且易于重复的测量方法可能是早期乳腺癌保守治疗后美容效果的一个有用的客观指标。
