French National Institute of Prevention and Health Education, Scientific Affairs Department, 42 boulevard de la Libération, 93203 Saint-Denis cedex, France.
Drug Alcohol Depend. 2013 Nov 1;133(1):254-61. doi: 10.1016/j.drugalcdep.2013.04.026. Epub 2013 May 30.
Monitoring of emerging modes of drug consumption in France has identified new patterns of injection among youths with diverse social backgrounds, which may explain the persistence of high rates of hepatitis C virus infection. The circumstances surrounding the first injection have been poorly documented in the group of heavy drug users and in the context of the French opioid substitution treatment (OST) policy that provides expanded access to high-dosage buprenorphine (BHD) METHODS: An Internet survey (Priminject) was conducted from October 2010 to March 2011 with French drug users. Four time periods were compared based on critical dates throughout the implementation of the Harm Reduction Policy in France.
Compared with drug users who injected for the first time prior to 1995, the aspects of drug use for users who recently injected for the first time were as follows: (1) experimentation with miscellaneous drugs before the first injection; (2) an older age at the time of first injection; (3) heroin as the drug of choice for an individual's first injection, notwithstanding the increased usage of stimulant drugs; (4) BHD did not appear to be a pathway to injection; and (5) an increased number of users who injected their first time alone, without the help or presence of another individual.
The PrimInject study showed that there is a group of injection drug users that is larger than the group of injection drug users observed in previous studies; therefore, it is necessary to diversify programs to reach the entire spectrum of high-risk users.
法国对新兴毒品使用模式的监测发现,具有不同社会背景的青少年中出现了新的注射方式,这可能解释了丙型肝炎病毒感染率居高不下的原因。在重度吸毒者群体中,以及在提供扩大高剂量丁丙诺啡(BHD)使用机会的法国阿片类物质替代治疗(OST)政策背景下,首次注射的情况记录甚少。
2010 年 10 月至 2011 年 3 月,通过互联网对法国吸毒者进行了一项调查(Priminject)。根据法国减少伤害政策实施过程中的关键日期,比较了四个时期。
与 1995 年以前首次注射的吸毒者相比,最近首次注射的吸毒者在首次使用毒品方面的情况如下:(1)首次注射前曾尝试过各种药物;(2)首次注射时年龄较大;(3)尽管兴奋剂的使用有所增加,但海洛因仍是首次注射的首选药物;(4)BHD 似乎不是导致注射的途径;(5)首次注射时独自注射的吸毒者数量增加,没有其他人帮助或在场。
PrimInject 研究表明,有一个比以前研究中观察到的更大的注射毒品使用者群体;因此,有必要多样化方案,以覆盖所有高风险使用者。