Graduate Institute of Public Health, China Medical University, Taichung 40402, Taiwan.
Bone. 2013 Sep;56(1):147-53. doi: 10.1016/j.bone.2013.05.015. Epub 2013 May 28.
Osteoporotic hip fractures cause high mortality in the elderly population. However, few population studies reported the long-term mortality of hip fracture among the elderly in Asian population. This study assessed the incidence, excess mortality, and risk factors after osteoporotic hip fractures through inpatients aged 60 years or older. A total of 143,595 patients with hip fracture were selected from Taiwan National Health Insurance database in the years 1999 to 2009 and followed up until the end of 2010. Annual incidence, mortality and SMR, and mortality and SMR at different periods after fracture were measured. From 1999 to 2005, hip fracture incidence gradually increased and then fluctuated after 2006. From 1999 to 2009, the male-to-female ratio of annual incidence increased from 0.60 to 0.66, annual mortality for hip fracture decreased from 18.10% to 13.98%, male-to-female ratio of annual mortality increased from 1.38 to 1.64, and annual SMR decreased from 13.80 to 2.98. Follow-up SMR at one, two, five, and ten years post-fracture was 9.67, 5.28, 3.31, and 2.89, respectively. Females had higher follow-up SMR in the younger age groups (60-69 yr of age) but lower follow-up SMR in the older age groups (over 80 yr of age) compared with males. Among the studied patients, incidence is gradually decreasing along with annual mortality and SMR. Hip fracture affects short-term but not long-term mortality.
骨质疏松性髋部骨折导致老年人群死亡率较高。然而,很少有针对亚洲人群的研究报告老年人髋部骨折的长期死亡率。本研究通过对 1999 年至 2009 年年龄在 60 岁或以上的住院患者评估骨质疏松性髋部骨折的发生率、超额死亡率和危险因素。从台湾全民健康保险数据库中选择了 143595 名髋部骨折患者,并随访至 2010 年底。测量了每年的发病率、死亡率和 SMR,以及骨折后不同时期的死亡率和 SMR。1999 年至 2005 年,髋部骨折的发病率逐渐增加,2006 年后波动。1999 年至 2009 年,男性与女性的年发病率比从 0.60 增加到 0.66,髋部骨折的年死亡率从 18.10%降至 13.98%,男性与女性的年死亡率比从 1.38 增加到 1.64,年 SMR 从 13.80 降至 2.98。骨折后 1、2、5 和 10 年的随访 SMR 分别为 9.67、5.28、3.31 和 2.89。与男性相比,女性在年龄较小的组(60-69 岁)的随访 SMR 较高,而在年龄较大的组(80 岁以上)的随访 SMR 较低。在研究患者中,发病率随着每年的死亡率和 SMR 逐渐下降。髋部骨折影响短期但不影响长期死亡率。