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伪装成喉癌的喉平滑肌肉瘤。

Laryngeal leiomyosarcoma masquerading as laryngeal carcinoma.

作者信息

Singh Lavleen, Mallick Saumyaranjan, Singh Shuchita, Safaya Rajni

机构信息

Department of Pathology, All India Institute of Medical Sciences, New Delhi, Delhi, India.

出版信息

BMJ Case Rep. 2013 May 31;2013:bcr2013009231. doi: 10.1136/bcr-2013-009231.

Abstract

Laryngeal leiomyosarcoma is an exceedingly rare malignant tumour, with fewer than 50 reported cases in scientific literature. Diagnosis is based on immunohistochemistry, supplemented with ultrastructural studies, if required. It is aggressive and associated with variable survival outcomes. A 63-year-old man presented with hoarseness for 7 months and breathlessness for 3 months. Imaging showed a well-defined 3 cm glottic mass. Total laryngectomy was performed. The histopathological examination showed features of leiomyosarcoma. The index case has been presented owing to its rarity, variable clinical manifestations and diagnostic dilemmas and to stress upon the importance of ancillary techniques for confirmation.

摘要

喉平滑肌肉瘤是一种极其罕见的恶性肿瘤,科学文献中报道的病例不足50例。诊断基于免疫组织化学,必要时辅以超微结构研究。它具有侵袭性,生存结果各不相同。一名63岁男性出现声音嘶哑7个月,呼吸困难3个月。影像学检查显示声门区有一个边界清晰的3厘米肿块。进行了全喉切除术。组织病理学检查显示为平滑肌肉瘤特征。报告该病例是因其罕见性、多样的临床表现和诊断困境,并强调辅助技术对确诊的重要性。

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