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喉上皮样平滑肌肉瘤

Epithelioid leiomyosarcoma of the larynx.

作者信息

Sindwani R, Matthews T W, Thomas J, Venkatesan V M

机构信息

Department of Otolaryngology, St. Joseph's Health Centre, University of Western Ontario, London, Canada.

出版信息

Head Neck. 1998 Sep;20(6):563-7. doi: 10.1002/(sici)1097-0347(199809)20:6<563::aid-hed12>3.0.co;2-l.

Abstract

BACKGROUND

Tumors of smooth muscle origin are rare in the upper aerodigestive tract, due to the paucity of smooth muscle in the area. A review of the literature revealed 34 reported cases of leiomyoma, 9 cases of leiomyosarcoma, and only 2 cases of epithelioid leiomyoma arising in the larynx.

METHODS

A case report of an epithelioid leiomyosarcoma arising in the right piriform fossa of a 38-year-old man is presented.

RESULTS

The tumor was treated with conservative surgical resection and postoperative radiotherapy. There was no evidence of locoregional recurrence 2 years postsurgery, and laryngeal function was preserved.

CONCLUSIONS

To our knowledge, this is the third case of a laryngeal epithelioid smooth muscle tumor to be reported in the world literature and the only documentation of an epithelioid leiomyosarcoma arising in the larynx.

摘要

背景

由于上消化道气道区域平滑肌数量稀少,平滑肌源性肿瘤在上消化道气道区域较为罕见。文献回顾显示,有34例平滑肌瘤、9例平滑肌肉瘤的报道,而起源于喉部的上皮样平滑肌瘤仅有2例。

方法

本文报告了一例38岁男性右侧梨状窝上皮样平滑肌肉瘤的病例。

结果

该肿瘤采用保守性手术切除及术后放疗进行治疗。术后2年无局部区域复发迹象,且保留了喉功能。

结论

据我们所知,这是世界文献中报道的第三例喉部上皮样平滑肌肿瘤,也是喉部起源的上皮样平滑肌肉瘤的唯一记录。

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