Saad Wael E A
Division of Vascular Interventional Radiology, Department of Radiology and Medical Imaging, University of Virginia Health System, Charlottesville, Virginia.
Semin Intervent Radiol. 2012 Jun;29(2):118-28. doi: 10.1055/s-0032-1312573.
Patients with gastric variceal bleeding require a multidisciplinary team approach including hepatologists, endoscopists, diagnostic radiologists, and interventional radiologists. Upper gastrointestinal endoscopy is the first-line diagnostic and management tool for bleeding gastric varices, as it is in all upper gastrointestinal bleeding scenarios. In the United States when endoscopy fails to control gastric variceal bleeding, a transjugular intrahepatic portosystemic shunt (TIPS) traditionally is performed along the classic teachings of decompressing the portal circulation. However, TIPS has not shown the same effectiveness in controlling gastric variceal bleeding that it has with esophageal variceal bleeding. For the past 2 decades, the balloon-occluded retrograde transvenous obliteration (BRTO) procedure has become common practice in Asia for the management of gastric varices. BRTO is gaining popularity in the United States. It has been shown to be effective in controlling gastric variceal bleeding with low rebleed rates. BRTO has many advantages over TIPS in that it is less invasive and can be performed on patients with poor hepatic reserve and those with encephalopathy (and may even improve both). However, its by-product is occlusion of a spontaneous hepatofugal (TIPS equivalent) shunt, and thus it is contradictory to the traditional American doctrine of portal decompression. Indeed, BRTO causes an increase in portal hypertension, with potential aggravation of esophageal varices and ascites. This article discusses the concept, technique, and outcomes of BRTO within the broader management of gastric varices.
胃静脉曲张出血患者需要多学科团队的治疗方法,包括肝病专家、内镜医师、诊断放射科医生和介入放射科医生。上消化道内镜检查是治疗胃静脉曲张出血的一线诊断和治疗工具,就像在所有上消化道出血情况中一样。在美国,当内镜检查无法控制胃静脉曲张出血时,传统上会按照经典的门静脉循环减压原则进行经颈静脉肝内门体分流术(TIPS)。然而,TIPS在控制胃静脉曲张出血方面并未显示出与控制食管静脉曲张出血相同的效果。在过去20年里,球囊闭塞逆行静脉栓塞术(BRTO)已成为亚洲治疗胃静脉曲张的常用方法。BRTO在美国也越来越受欢迎。它已被证明在控制胃静脉曲张出血方面有效,再出血率低。与TIPS相比,BRTO有许多优点,因为它侵入性较小,可用于肝储备功能差和患有脑病的患者(甚至可能改善这两种情况)。然而,其副产品是闭塞自发性肝静脉分流(相当于TIPS),因此与美国传统的门静脉减压学说相矛盾。事实上,BRTO会导致门静脉高压升高,可能加重食管静脉曲张和腹水。本文在更广泛的胃静脉曲张管理范围内讨论了BRTO的概念、技术和结果。