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胃静脉曲张的血管内治疗

Endovascular management of gastric varices.

作者信息

Saad Wael E

机构信息

Department of Radiology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

出版信息

Clin Liver Dis. 2014 Nov;18(4):829-51. doi: 10.1016/j.cld.2014.07.005. Epub 2014 Oct 16.

DOI:10.1016/j.cld.2014.07.005
PMID:25438286
Abstract

Bleeding from gastric varices is a major complication of portal hypertension. Although less common than bleeding associated with esophageal varices, gastric variceal bleeding has a higher mortality. From an endovascular perspective,transjugular intrahepatic portosystemic shunts (TIPS) to decompress the portal circulation and/or balloon-occluded retrograde transvenous obliteration (BRTO) are utilized to address bleeding gastric varices. Until recently, there was a clear medical cultural divide between the strategy of decompressing the portal circulation (TIPS creation, for example) and transvenous obliteration for the management of gastric varices. However, the practice of BRTO is gaining acceptance in the United States and its practice is spreading rapidly. Recently, the American College of Radiology has identified BRTO to be a viable alternative to TIPS in particular anatomical and clinical scenarios. However, the anatomical and clinical applications of BRTO were not defined beyond the conservative approach of resorting to BRTO in non-TIPS candidates. The article discusses the outcomes of BRTO and TIPS for the management of gastric varices individually or in combination. Definitions, endovascular technical concepts and contemporary vascular classifications of gastric variceal systems are described in order to help grasp the complexity of the hemodynamic pathology and hopefully help define the pathology better for future reporting and lay the ground for more defined stratification of patients not only based on comorbidity and hepatic reserve but on anatomy and hemodynamic classifications.

摘要

胃静脉曲张出血是门静脉高压的主要并发症。虽然胃静脉曲张出血比食管静脉曲张出血少见,但死亡率更高。从血管内介入角度来看,经颈静脉肝内门体分流术(TIPS)用于减压门静脉循环和/或球囊闭塞逆行静脉栓塞术(BRTO)用于治疗胃静脉曲张出血。直到最近,在胃静脉曲张治疗策略上,门静脉循环减压策略(例如创建TIPS)和经静脉闭塞策略之间还存在明显的医学文化差异。然而,BRTO在美国越来越被接受,其应用正在迅速推广。最近,美国放射学会已确定在特定的解剖和临床情况下,BRTO是TIPS的可行替代方案。然而,除了在非TIPS适用患者中采用BRTO这种保守方法外,BRTO的解剖学和临床应用尚未明确界定。本文讨论了BRTO和TIPS单独或联合治疗胃静脉曲张的疗效。描述了胃静脉曲张系统的定义、血管内技术概念和当代血管分类,以帮助理解血流动力学病理的复杂性,并希望能更好地界定病理情况,以便未来报告,并为不仅基于合并症和肝储备,还基于解剖学和血流动力学分类的更明确的患者分层奠定基础。

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