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[使用长期低温保存角膜的穿透性角膜移植术]

[Penetrating keratoplasty with long-term cryopreserved corneas].

作者信息

Wang C F

机构信息

Department of Ophthalmology, Affiliated Hospital to Qingdao Medical College, Shandong Province.

出版信息

Zhonghua Yan Ke Za Zhi. 1990 Jan;26(1):17-20.

PMID:2373028
Abstract

Since March 1986, the authors studied the simplified corneal cryopreservation technique with their "QL Bio-Freezer". After successful animal experiments, 34 patients (35 eyes) were performed penetrating keratoplasty with human cadaver corneas cryopreserved 9 to 473 days, averaging 108 days. After following-ups of 1 1/2 to 28 months, 22 of the corneal grafts remained clear, 6 semitransparent, and 7 cloudy. A total of 25 eyes had their visual acuity improved significantly. The results show that the cornea cryopreservation technique with the simplified "two-step" method is a noteworthy clinical practice.

摘要

自1986年3月起,作者们使用他们的“QL生物冷冻仪”研究了简化的角膜冷冻保存技术。在动物实验成功后,对34例患者(35只眼)进行了穿透性角膜移植术,所用的人尸体角膜冷冻保存了9至473天,平均108天。经过1个半月至28个月的随访,22只角膜移植片保持透明,6只半透明,7只混浊。共有25只眼的视力有显著提高。结果表明,采用简化“两步法”的角膜冷冻保存技术是一项值得关注的临床实践。

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[Penetrating keratoplasty with long-term cryopreserved corneas].[使用长期低温保存角膜的穿透性角膜移植术]
Zhonghua Yan Ke Za Zhi. 1990 Jan;26(1):17-20.
2
Evaluation of penetrating keratoplasties with long-term cryopreserved corneas using simplified method.使用简化方法评估长期低温保存角膜的穿透性角膜移植术。
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Penetrating keratoplasty with small-diameter and glycerin-cryopreserved grafts for eccentric corneal perforations.采用小直径甘油冷冻保存移植物的穿透性角膜移植术治疗偏心性角膜穿孔。
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[Medium-term preservation of human corneas in an enriched culture medium at +37 degrees Centigrade].[在37摄氏度的富集培养基中对人角膜进行中期保存]
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[An experimental study on corneal nerve regeneration after penetrating keratoplasty with long-term cryopreserved rabbit corneas].
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[The improvement on related condition of corneal cryopreservation and roles of cryopreserved corneas in emergent keratoplasty].[角膜冷冻保存相关条件的改善及冷冻保存角膜在急诊角膜移植术中的作用]
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[Comparing cryopreserved with fresh corneas on clinical application in penetrating keratoplasty].[穿透性角膜移植术中冷冻保存角膜与新鲜角膜临床应用的比较]
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Re-examination of organ-cultured, cryopreserved human corneal grafts after 27 years.27年后对器官培养、冷冻保存的人类角膜移植片的重新检查。
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Ophthalmol Ther. 2024 Apr;13(4):979-994. doi: 10.1007/s40123-024-00889-z. Epub 2024 Feb 12.