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大肠杆菌葡萄糖/乳糖代谢基因调控自适应动力学的类量子模型。

Quantum-like model for the adaptive dynamics of the genetic regulation of E. coli's metabolism of glucose/lactose.

作者信息

Asano Masanari, Basieva Irina, Khrennikov Andrei, Ohya Masanori, Tanaka Yoshiharu, Yamato Ichiro

机构信息

Department of Information Sciences, Tokyo University of Science, Yamasaki 2641, Noda-shi, Chiba, 278-8510 Japan.

出版信息

Syst Synth Biol. 2012 Jun;6(1-2):1-7. doi: 10.1007/s11693-012-9091-1. Epub 2012 Apr 11.

Abstract

We developed a quantum-like model describing the gene regulation of glucose/lactose metabolism in a bacterium, Escherichia coli. Our quantum-like model can be considered as a kind of the operational formalism for microbiology and genetics. Instead of trying to describe processes in a cell in the very detail, we propose a formal operator description. Such a description may be very useful in situation in which the detailed description of processes is impossible or extremely complicated. We analyze statistical data obtained from experiments, and we compute the degree of E. coli's preference within adaptive dynamics. It is known that there are several types of E. coli characterized by the metabolic system. We demonstrate that the same type of E. coli can be described by the well determined operators; we find invariant operator quantities characterizing each type. Such invariant quantities can be calculated from the obtained statistical data.

摘要

我们开发了一种类量子模型,用于描述细菌大肠杆菌中葡萄糖/乳糖代谢的基因调控。我们的类量子模型可被视为微生物学和遗传学的一种操作形式体系。我们并非试图非常详细地描述细胞内的过程,而是提出一种形式化的算子描述。在过程的详细描述不可能或极其复杂的情况下,这种描述可能非常有用。我们分析从实验中获得的统计数据,并计算大肠杆菌在适应性动力学中的偏好程度。已知有几种以代谢系统为特征的大肠杆菌类型。我们证明,同一类型的大肠杆菌可以用确定的算子来描述;我们找到了表征每种类型的不变算子量。这种不变量可以从获得的统计数据中计算出来。

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