Department of Pneumonology, General Army Hospital of Athens, Athens, Greece;
J Gastrointest Oncol. 2013 Jun;4(2):E11-5. doi: 10.3978/j.issn.2078-6891.2012.057.
Lung cancer metastasizing to gastrointestinal (GI)-tract is a rare event. Gastric metastasis is usually asymptomatic but when mucosal in location it may cause symptoms as demonstrated in the current case. This report describes a 60-year old male who was admitted for evaluation of a left upper lobe lung mass with associated bilateral nodular opacities and mediastinal lymphadenopathy. After thorough work-up the diagnosis of advanced lung adenocarcinoma was made. During hospitalization period and prior to starting chemotherapy, he exhibited upper gastrointentinal bleeding. Esophagogastroduodenoscopy revealed an ulcerative lesion in the gastric corpus representing metastasis of the primary lung carcinoma that ensued from immunohistochemical analysis. Clinical, pathological and therapeutic aspects of this uncommon site of extrathoracic metastatic disease are discussed, emphasizing the importance of the immunohistochemistry in the differential diagnosis of lung carcinomas whether primary or secondary to the lung.
肺癌转移至胃肠道（GI）是一种罕见的事件。胃转移通常无症状，但当位于黏膜时，可能会引起症状，如当前病例所示。本报告描述了一名 60 岁男性，因左肺上叶肿块伴双侧结节性混浊和纵隔淋巴结肿大入院治疗。经过全面检查，诊断为晚期肺腺癌。在住院期间和开始化疗之前，他出现上消化道出血。食管胃十二指肠镜检查显示胃体部有一个溃疡性病变，代表原发性肺癌的转移，这是通过免疫组织化学分析得出的。讨论了这种非胸部远处转移疾病罕见部位的临床、病理和治疗方面，强调了免疫组织化学在肺腺癌的鉴别诊断中的重要性，无论是原发性还是继发性于肺部。
