Health Intelligence Unit, Prevention and Population Health Branch, Victorian Government Department of Health Office of the Deputy Vice Chancellor (Research), Monash University, Victoria.
Aust N Z J Public Health. 2013 Jun;37(3):233-7. doi: 10.1111/1753-6405.12064.
To estimate blood lead levels (BLLs) in the adult Victorian population and compare the distribution of BLLs with the current national reference level to better inform public health prevention and management of lead toxicity.
Population-based cross-sectional health measurement survey of 50 randomly selected Census Collection Districts (CDs) throughout Victoria. The Victorian Health Monitor (VHM) was conducted over 12 months from May 2009 to April 2010. One eligible person (aged 18-75 years) from each household selected within each CD was randomly selected to participate. Persons with an intellectual disability and pregnant women were excluded from the sampling frame. BLLs were obtained from 3,622 of the 3,653 (99%) VHM participants.
The geometric mean and median BLLs from the adult sample were 0.070 μmol/L (95%CI, 0.068-0.073) and 0.05 μmol/L (range: 0.05 to 1.22 μmol/L), respectively. Elevated BLLs (≥0.483 μmol/L or ≥10 μg/dL) were identified in 19 participants (0.7%; 95%CI, 0.3-1.6). Additionally, 86 participants (1.8%; 95%CI, 1.3-2.4) were identified with BLLs between 0.242 and <0.483 μmol/L (5 to <10 μg/dL). The geometric mean BLL was significantly higher for males, compared with females (0.077 μmol/L vs 0.064 μmol/L; p<0.001). BLLs increased significantly with age for both sexes.
The first population estimates of BLLs in Victorian adults indicate the average adult BLL to be well below the current national reference level. However, some groups of the population have BLLs at which adverse effects may occur. Implications : The results provide baseline estimates for future population health surveillance and comparison with studies of at-risk groups.
评估维多利亚州成年人群的血铅水平(BLL),并将 BLL 分布与当前国家参考水平进行比较,以更好地为铅毒性的公共卫生预防和管理提供信息。
这是一项基于人群的横断面健康测量调查,在维多利亚州的 50 个随机选择的人口普查区(CD)中进行。维多利亚健康监测(VHM)于 2009 年 5 月至 2010 年 4 月进行了 12 个月。从每个 CD 中选择的每个家庭中随机选择一名符合条件的(年龄在 18-75 岁之间)成年人参与。抽样框架中排除了智障人士和孕妇。从 3622 名符合条件的 VHM 参与者中获得了 BLL 数据。
成年样本的几何平均值和中位数 BLL 分别为 0.070 μmol/L(95%CI,0.068-0.073)和 0.05 μmol/L(范围:0.05-1.22 μmol/L)。在 19 名参与者(0.7%;95%CI,0.3-1.6)中发现了升高的 BLL(≥0.483 μmol/L 或≥10μg/dL)。此外,在 86 名参与者(1.8%;95%CI,1.3-2.4)中发现 BLL 处于 0.242 至<0.483 μmol/L(5 至<10μg/dL)之间。与女性相比,男性的几何平均值 BLL 明显更高(0.077 μmol/L 与 0.064 μmol/L;p<0.001)。BLL 随性别和年龄显著增加。
维多利亚州成年人首次进行的 BLL 人群估计表明,普通成年人的 BLL 远低于当前的国家参考水平。然而,一些人群的 BLL 处于可能出现不良反应的水平。 意义:研究结果为未来的人群健康监测提供了基线估计,并与高危人群的研究进行了比较。