Shigematsu Y, Mori I, Nakai A, Kikawa Y, Kuriyama M, Konishi Y, Fujii T, Sudo M
Department of Paediatrics, Fukui Medical School, Japan.
Eur J Pediatr. 1990 Jun;149(9):659-60. doi: 10.1007/BF02034758.
A 10-month-old girl with mild developmental delay became hemiplegic after seizures. Cranial CT scan and magnetic resonance imaging (MRI) revealed no lesions related to vascular diseases, but brain atrophy on the right side was remarkable. Digital subtraction angiography showed slightly decreased visualization of peripheral branches of the right medial cerebral artery. Propionic acidaemia was diagnosed on the basis of high plasma levels of propionic acid and its metabolites and the elevated urinary excretion of these acids. With therapy, the levels of these acids fell, and her left hemiplegia disappeared 3 months later.
一名10个月大、有轻度发育迟缓的女孩在癫痫发作后出现偏瘫。头颅CT扫描和磁共振成像（MRI）未发现与血管疾病相关的病变，但右侧脑萎缩明显。数字减影血管造影显示右侧大脑中动脉外周分支的显影略有减少。根据血浆中丙酸及其代谢产物水平升高以及这些酸在尿液中的排泄增加，诊断为丙酸血症。经过治疗，这些酸的水平下降，3个月后她的左侧偏瘫消失。
