Cimino G, Crispino A, Di Marzo V, Gavagnin M, Ros J D
Istituto per la Chimica di Molecole d'Interesse Biologico, Napoli, Italy.
Experientia. 1990 Jul 15;46(7):767-70. doi: 10.1007/BF01939963.
The ethereal extract of the mucous secretion from the opisthobranch mollusc Oxynoe olivacea was examined and found to contain two novel ichthyotoxic compounds, named oxytoxin 1 and 2 (1,2). The structures of 1 and 2 are closely related to the metabolites previously isolated from the alga Caulerpa prolifera. The activity of the most stable compound was studied in order to investigate the possibility of a further biological role for these metabolites, which represent an uncommon example of bioactive molecules produced in vivo from a dietary precursor.
对后鳃亚纲软体动物奥克西诺橄榄螺黏液分泌物的乙醚提取物进行了检测，发现其中含有两种新型鱼毒素化合物，分别命名为氧毒素1和2（1,2）。化合物1和2的结构与先前从藻类粗枝软骨藻中分离出的代谢产物密切相关。对最稳定化合物的活性进行了研究，以探讨这些代谢产物可能具有的进一步生物学作用，这些代谢产物代表了由膳食前体在体内产生的生物活性分子的一个罕见例子。
