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一种蓝绿藻毒素:与石房蛤毒素的相似性。

Toxins of a blue-green alga: similarity to saxitoxin.

作者信息

Jackim E, Gentile J

出版信息

Science. 1968 Nov 22;162(3856):915-6. doi: 10.1126/science.162.3856.915.

DOI:10.1126/science.162.3856.915
PMID:5684499
Abstract

Toxins were isolated from the freshwater blue-green alga Aphanizomenon flos-aquae. The toxic fractions were characterized by paper and thin-layer chromatography, isolation characteristics, infrared spectra, physiological activity, and reactivity with specific color reagents. The toxic fractions appear to be similar, if not identical, to saxitoxin (paralytic shellfish toxin), which is produced by the marine dinoflagellate Gonyaulax catenella.

摘要

毒素是从淡水蓝绿藻水华束丝藻中分离出来的。通过纸色谱法、薄层色谱法、分离特性、红外光谱、生理活性以及与特定显色试剂的反应对有毒馏分进行了表征。这些有毒馏分似乎与由海洋甲藻链状亚历山大藻产生的石房蛤毒素(麻痹性贝类毒素)相似,即便不是完全相同。

相似文献

1
Toxins of a blue-green alga: similarity to saxitoxin.一种蓝绿藻毒素:与石房蛤毒素的相似性。
Science. 1968 Nov 22;162(3856):915-6. doi: 10.1126/science.162.3856.915.
2
Comparison of the toxins of the blue-green alga Aphanizomenon flos-aquae with the Gonyaulax toxins.蓝绿藻水华束丝藻毒素与多甲藻毒素的比较。
Toxicon. 1982;20(4):747-52. doi: 10.1016/0041-0101(82)90122-2.
3
Paralytic shellfish poisons produced by the freshwater cyanobacterium Aphanizomenon flos-aquae NH-5.由淡水蓝藻水华鱼腥藻NH-5产生的麻痹性贝类毒素。
Toxicon. 1986;24(2):175-86. doi: 10.1016/0041-0101(86)90120-0.
4
Demonstration of a toxin from Aphanizomenon flos-aquae (L.) Ralfs.
Can J Microbiol. 1968 Nov;14(11):1199-204. doi: 10.1139/m68-201.
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Presence of four toxins in red tide infested clams and cultured Gonyaulax tamarensis cells.在受赤潮影响的蛤类和养殖的塔玛亚历山大藻细胞中存在四种毒素。
Biochem Biophys Res Commun. 1975 Sep 16;66(2):731-7. doi: 10.1016/0006-291x(75)90571-9.
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Palytoxin: a new marine toxin from a coelenterate.刺尾鱼毒素:一种来自腔肠动物的新型海洋毒素。
Science. 1971 Apr 30;172(3982):495-8. doi: 10.1126/science.172.3982.495.
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Comparison of crab toxin with saxitoxin and tetrodotoxin.蟹毒素与石房蛤毒素和河豚毒素的比较。
Toxicon. 1968 Oct;6(2):113-7. doi: 10.1016/0041-0101(68)90029-9.
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The purification and characterization of the poison produced by Gonyaulax catenella in axenic culture.在无菌培养条件下对链状裸甲藻产生的毒素进行纯化与鉴定。
Biochemistry. 1966 Apr;5(4):1191-5. doi: 10.1021/bi00868a011.
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Isolation of Gonyaulax tamarensis toxins from soft shell clams (Mya arenaria) and a thin-layer chromatographic-fluorometric method for their detection.
J Agric Food Chem. 1976 Jan-Feb;24(1):107-11. doi: 10.1021/jf60203a004.
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Zebrafish neurotoxicity from aphantoxins--cyanobacterial paralytic shellfish poisons (PSPs) from Aphanizomenon flos-aquae DC-1.斑马鱼神经毒性的阿朴菲类毒素——来自束丝藻的麻痹性贝类毒素(PSPs)。
Environ Toxicol. 2013 May;28(5):239-54. doi: 10.1002/tox.20714. Epub 2011 Jun 24.

引用本文的文献

1
A Fresh Perspective on Cyanobacterial Paralytic Shellfish Poisoning Toxins: History, Methodology, and Toxicology.蓝藻麻痹性贝类中毒毒素的全新视角:历史、方法与毒理学
Mar Drugs. 2025 Jun 27;23(7):271. doi: 10.3390/md23070271.
2
The Potential of Allelochemicals from Microalgae for Biopesticides.微藻化感物质用于生物农药的潜力
Plants (Basel). 2023 May 6;12(9):1896. doi: 10.3390/plants12091896.
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Emerging Lyngbya wollei toxins: A new high resolution mass spectrometry method to elucidate a potential environmental threat.新兴 Lyngbya wollei 毒素:一种新的高分辨率质谱法,用于阐明潜在的环境威胁。
Harmful Algae. 2019 Dec;90:101700. doi: 10.1016/j.hal.2019.101700. Epub 2019 Nov 20.
4
Non-traditional vectors for paralytic shellfish poisoning.麻痹性贝类中毒的非传统载体
Mar Drugs. 2008 Jun 10;6(2):308-48. doi: 10.3390/md20080015.
5
Paralytic Shellfish Toxins in Protogonyaulax tamarensis and Protogonyaulax catenella in Axenic Culture.塔玛亚历山大藻和链状亚历山大藻在无菌培养中的麻痹性贝类毒素。
Plant Physiol. 1988 Dec;88(4):1285-90. doi: 10.1104/pp.88.4.1285.
6
Algal toxins.藻毒素
Microbiol Rev. 1978 Dec;42(4):725-46. doi: 10.1128/mr.42.4.725-746.1978.
7
Two toxins from a poisonous sample of mussels Mytilus edulis.来自贻贝可食贻贝有毒样本的两种毒素。
Br J Pharmacol. 1970 Dec;40(4):847-65. doi: 10.1111/j.1476-5381.1970.tb10660.x.
8
Physiology and cytological chemistry blue-green algae.蓝藻的生理学与细胞化学
Bacteriol Rev. 1973 Mar;37(1):32-101. doi: 10.1128/br.37.1.32-101.1973.
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Properties and use of botulinum toxin and other microbial neurotoxins in medicine.肉毒杆菌毒素及其他微生物神经毒素在医学中的特性与应用。
Microbiol Rev. 1992 Mar;56(1):80-99. doi: 10.1128/mr.56.1.80-99.1992.