Carral Liliana, Kaufer Federico, Olejnik Patricia, Freuler Cristina, Durlach Ricardo
Centro de Toxoplasmosis y otras Zoonosis, Hospital Alemán de Buenos Aires, Argentina.
Medicina (B Aires). 2013;73(3):238-42.
The prevention of congenital toxoplasmosis is based on providing information to women, serologic diagnosis and treatment of the infected mother and child. In this article we present the results of 12 years of implementation of a congenital toxoplasmosis prevention program in which we measured the mother's infection incidence rate, the transmission rate and the number and severity of infection in newborns. The study was performed on 12035 pregnant women in the period 2000-2011. The prevalence rate of antibodies against Toxoplasma gondii was 18.33% (2206/12035). Thirty-seven out of 9792 susceptible women presented acute infection and the mother's infection incidence rate was 3.78 per 1000 births. The transplacental transmission rate was 5.4% (2/37). Two newborns presented congenital toxoplasmosis infection, one had no clinical signs while the other presented strabismus and chorioretinitis. Thirty-five infected mothers and the two children with congenital infection were treated. The transmission rates obtained allow consider this prevention program as a valid resource to minimize the impact of congenital toxoplasmosis.
先天性弓形虫病的预防基于向女性提供信息、对感染的母婴进行血清学诊断和治疗。在本文中，我们展示了一项先天性弓形虫病预防计划实施12年的结果，在该计划中，我们测量了母亲的感染发病率、传播率以及新生儿感染的数量和严重程度。该研究于2000年至2011年期间对12035名孕妇进行。抗弓形虫抗体的患病率为18.33%（2206/12035）。9792名易感女性中有37名出现急性感染，母亲的感染发病率为每1000例分娩3.78例。经胎盘传播率为5.4%（2/37）。两名新生儿出现先天性弓形虫病感染，一名没有临床症状，另一名出现斜视和脉络膜视网膜炎。35名感染母亲和两名先天性感染儿童接受了治疗。所获得的传播率使我们可以认为该预防计划是减少先天性弓形虫病影响的有效资源。
