Josephs Lynn K, Coker Robina K, Thomas Mike
Primary Care Research, Aldermoor Health Centre, University of Southampton, Southampton, UK.
Prim Care Respir J. 2013 Jun;22(2):234-8. doi: 10.4104/pcrj.2013.00046.
Air travel poses medical challenges to passengers with respiratory disease, principally because of exposure to a hypobaric environment. In 2002 the British Thoracic Society published recommendations for adults and children with respiratory disease planning air travel, with a web update in 2004. New full recommendations and a summary were published in 2011, containing key recommendations for the assessment of high-risk patients and identification of those likely to require in-flight supplemental oxygen. This paper highlights the aspects of particular relevance to primary care practitioners with the following key points: (1) At cabin altitudes of 8000 feet (the usual upper limit of in-flight cabin pressure, equivalent to 0.75 atmospheres) the partial pressure of oxygen falls to the equivalent of breathing 15.1% oxygen at sea level. Arterial oxygen tension falls in all passengers; in patients with respiratory disease, altitude may worsen preexisting hypoxaemia. (2) Altitude exposure also influences the volume of any air in cavities, where pressure x volume remain constant (Boyle's law), so that a pneumothorax or closed lung bulla will expand and may cause respiratory distress. Similarly, barotrauma may affect the middle ear or sinuses if these cavities fail to equilibrate. (3) Patients with respiratory disease require clinical assessment and advice before air travel to: (a) optimise usual care; (b) consider contraindications to travel and possible need for in-flight oxygen; (c) consider the need for secondary care referral for further assessment; (d) discuss the risk of venous thromboembolism; and (e) discuss forward planning for the journey.
航空旅行给患有呼吸系统疾病的乘客带来了医学挑战,主要原因是他们会暴露在低压环境中。2002年,英国胸科学会发布了针对计划乘坐飞机旅行的患有呼吸系统疾病的成人和儿童的建议,并于2004年在网上进行了更新。2011年发布了新的完整建议和摘要,其中包含对高危患者进行评估以及确定可能需要机上补充氧气的患者的关键建议。本文重点介绍了与基层医疗从业者特别相关的方面,要点如下:(1)在机舱高度8000英尺(通常的飞行中机舱压力上限,相当于0.75个大气压)时,氧气分压降至相当于在海平面呼吸15.1%氧气时的水平。所有乘客动脉血氧张力都会下降;对于患有呼吸系统疾病的患者,高空可能会使原有的低氧血症恶化。(2)暴露在高空还会影响腔体内空气的体积,因为压力×体积保持不变(玻意耳定律),所以气胸或闭合性肺大疱会扩张并可能导致呼吸窘迫。同样,如果中耳或鼻窦腔未能平衡压力,气压伤可能会影响中耳或鼻窦。(3)患有呼吸系统疾病的患者在乘坐飞机旅行前需要进行临床评估并获得建议,以便:(a)优化日常护理;(b)考虑旅行禁忌和机上吸氧的可能需求;(c)考虑是否需要转诊至二级医疗机构进行进一步评估;(d)讨论静脉血栓栓塞的风险;(e)讨论旅程的前期规划。