Lee Jacky W Y, Wong Billy K T, Yick Doris W F, Wong Ian Y H, Yuen Can Y F, Lai Jimmy S M
The Department of Ophthalmology, The University of Hong Kong, Room 301 Level 3 Block B, Cyberport 4, 100 Cyberport Road, Hong Kong Special Administrative Region, China,
Int Ophthalmol. 2014 Apr;34(2):165-9. doi: 10.1007/s10792-013-9806-7. Epub 2013 Jun 4.
To investigate long-term clinical outcomes after acute angle closure in the Chinese population. A 10-year retrospective review of primary acute angle closure in Hong Kong Chinese to document patient demographics, treatment, and pre- and post-acute angle closure intraocular pressure (IOP) and visual acuity (VA). The year of attack was correlated with the timing of laser, last VA and IOP, and the number of anti-glaucoma eye drops. In 210 eyes (200 patients), 10 % had a simultaneous bilateral acute angle closure. VA improvement was noted in 68.6 % of eyes whilst 11.4 % were blinded. At 3.7 ± 2.4 years of follow-up, 49.5 % had IOP <21 mmHg with medication or surgery, 41.9 % needed anti-glaucoma eye drops, and 13.8 % had undergone trabeculectomy. The older the year of attack, the poorer the VA (r = 0.2, p = 0.03) and the longer the laser wait time (r = 0.3, p < 0.0001). VA outcome and laser promptness in acute angle closure has improved over the years. At 4 years after the attack, 50 % had normal IOP, 69 % had improved VA but 11 % were blinded.
旨在研究中国人群急性闭角型青光眼的长期临床结局。对香港华人原发性急性闭角型青光眼进行了为期10年的回顾性研究,以记录患者的人口统计学资料、治疗情况以及急性闭角型青光眼发作前后的眼压(IOP)和视力(VA)。发作年份与激光治疗时间、末次视力和眼压以及抗青光眼滴眼液的使用次数相关。在210只眼(200例患者)中,10%为双眼同时急性闭角型青光眼。68.6%的患眼视力得到改善,而11.4%的患眼失明。在3.7±2.4年的随访中,49.5%的患者通过药物或手术使眼压<21 mmHg,41.9%的患者需要使用抗青光眼滴眼液,13.8%的患者接受了小梁切除术。发作年份越晚,视力越差(r = 0.2,p = 0.03),激光等待时间越长(r = 0.3,p < 0.0001)。多年来,急性闭角型青光眼的视力结局和激光治疗及时性有所改善。发作后4年,50%的患者眼压正常,69%的患者视力改善,但11%的患者失明。