瓜环烯 A 和 B，来自圭亚那油棕种子的新碳骨架柠檬苦素。

Guianolides A and B, new carbon skeletal limonoids from the seeds of Carapa guianensis.

机构信息

Osaka University of Pharmaceutical Sciences , 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan, and Faculty of Pharmaceutical Sciences, Kinki University , 3-4-1 Kowakae, Higashiosaka, Osaka 577-8502, Japan.

出版信息

Org Lett. 2013 Jun 21;15(12):3018-21. doi: 10.1021/ol400924u. Epub 2013 Jun 4.

DOI:10.1021/ol400924u

PMID:23734934

Abstract

Two novel limonoids, named guianolides A (1) and B (2), were isolated from the seeds of Carapa guianensis AUBLET (Meliaceae). Their structures were established by spectroscopic analyses and X-ray crystallography. Guianolides A (1) and B (2) featured an unprecedented carbon skeleton via the formation of a C-11-C-21 bond.

摘要

从瓜那尼 Carapa guianensis AUBLET（楝科）的种子中分离得到两种新的柠檬苦素类化合物，命名为瓜那尼内酯 A（1）和 B（2）。通过光谱分析和 X 射线晶体学确定了它们的结构。瓜那尼内酯 A（1）和 B（2）通过形成 C-11-C-21 键呈现出前所未有的碳骨架。