Hassan Cesare, Repici Alessandro, Zullo Angelo, Kanakadandi Vijay, Sharma Prateek
Digestive Endoscopy Unit, IRCCS Istituto Clinico Humanitas, Via Manzoni 56, Rozzano, Milan 20089, Italy.
Gastrointest Endosc Clin N Am. 2013 Jul;23(3):663-78. doi: 10.1016/j.giec.2013.03.005. Epub 2013 May 14.
Colorectal cancer represents a major cause of mortality in Western countries, and population-based colonoscopy screening is supported by official guidelines. A significant determinant of the cost of colonoscopy screening/surveillance is driven by polypectomy of diminutive (≤5 mm) lesions. When considering the low prevalence of advanced neoplasia within diminutive polyps, the additional cost of pathologic examination is mainly justified by the need to differentiate between precancerous adenomatous versus hyperplastic polyps. The aim of this review is to summarize the data supporting the clinical application of a resect and discard strategy, also addressing the potential pitfalls associated with this approach.
结直肠癌是西方国家主要的死亡原因之一，基于人群的结肠镜筛查得到官方指南的支持。结肠镜筛查/监测成本的一个重要决定因素是微小（≤5毫米）病变的息肉切除术。考虑到微小息肉中晚期肿瘤的低患病率，病理检查的额外额外额外本综述的目的是总结支持切除并丢弃策略临床应用的数据，同时也探讨与该方法相关的潜在陷阱。
