Département de Pédiatrie, CHU Sainte-Justine, Université de Montréal, Montréal, Qué., Canada.
Neonatology. 2013;103(4):335-40. doi: 10.1159/000349933. Epub 2013 May 31.
Hemodynamic problems are common in neonatal intensive care. They occur in the context of incomplete myocardial and vascular development and in cardiovascular responses to interventions which are, as a result, limited and often uncertain and unpredictable. In this review, I outline the hemodynamic features of 4 neonatal conditions which often require intervention: (1) persistent pulmonary hypertension of the newborn, (2) cardiogenic shock (most commonly in the context of hypoxic ischemic injury), (3) sepsis and (4) low blood pressure in the transitional period of the extremely preterm infant. I also look at the evidence which exists for effective interventions and the most important research questions for the future.
新生儿重症监护中常见血流动力学问题。这些问题发生于心肌和血管发育不完全,以及对干预的心血管反应受限的背景下,因此,这些反应往往不确定且难以预测。在这篇综述中,我概述了 4 种常需干预的新生儿病症的血流动力学特征:(1)新生儿持续性肺动脉高压,(2)心源休克(最常见于缺氧缺血性损伤的情况下),(3)败血症,以及(4)极早产儿过渡期低血压。我还探讨了有效干预的现有证据,以及未来最重要的研究问题。