Dougherty Judith E
California State University, San Marcos, CA 92096, USA.
Crit Care Nurs Q. 2013 Jul-Sep;36(3):299-309. doi: 10.1097/CNQ.0b013e318294ea41.
Hyperbaric oxygen therapy has been approved for primary or adjunctive care in 14 indications. A hyperbaric environment exists when a patient's whole body is physically exposed to 100% oxygen and pressure that is greater than one atmosphere absolute. Hyperbaric oxygen therapy works through the ideal gas laws and is effective as an adjunctive therapy in the treatment of crush injuries. Oxygen is considered a drug and can have contraindications and adverse effects. Hyperbaric therapy works through several different mechanisms in the crush injury. Effects of hyperoxygenation, reduction of edema, infection control enhancement, blood vessel and collagen formation, and reduction of free radicals and reperfusion injury help in healing in patient with crush injuries.
高压氧疗法已被批准用于14种适应症的主要治疗或辅助治疗。当患者全身实际暴露于100%氧气且压力大于一个绝对大气压时，就会存在高压环境。高压氧疗法依据理想气体定律发挥作用，在挤压伤治疗中作为辅助疗法有效。氧气被视为一种药物，可能有禁忌症和不良反应。高压疗法在挤压伤中通过几种不同机制发挥作用。高氧作用、减轻水肿、增强感染控制、促进血管和胶原蛋白形成以及减少自由基和再灌注损伤，有助于挤压伤患者的愈合。
