Pichot Roman, Watson Richard L, Norton Ian T
Centre for Formulation Engineering, School of Chemical Engineering, University of Birmingham, Birmingham, Edgbaston B15 2TT, UK.
Int J Mol Sci. 2013 Jun 3;14(6):11767-94. doi: 10.3390/ijms140611767.
Phospholipids are one of the major structural elements of biological membranes. Due to their amphiphilic character, they can adopt various molecular assemblies when dispersed in water, such as bilayer vesicles or micelles, which give them unique interfacial properties and render them very attractive in terms of foam or emulsion stabilization. This article aims at reviewing the properties of phospholipids at the air/water and oil/water interfaces, as well as the recent advances in using these natural components as stabilizers, alone or in combination with other compounds such as proteins. A discussion regarding the challenges and opportunities offered by phospholipids-stabilized structure concludes the review.
磷脂是生物膜的主要结构成分之一。由于其两亲性,它们在分散于水中时可形成各种分子聚集体,如双层囊泡或胶束,这赋予它们独特的界面性质,并使其在泡沫或乳液稳定方面极具吸引力。本文旨在综述磷脂在气/水和油/水界面的性质,以及将这些天然成分单独或与蛋白质等其他化合物结合用作稳定剂的最新进展。关于磷脂稳定结构所带来的挑战和机遇的讨论作为本文的结语。