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同一儿童患有颅咽管瘤和表皮样肿瘤:一种罕见的关联。

Craniopharyngioma and epidermoid tumour in same child: a rare association.

作者信息

Singh Deepak Kumar, Singh Neha, Parihar Anit, Singh Ragini

机构信息

Department of Neurosurgery, Dr. RMLIMS, Lucknow, Uttar Pradesh, India.

出版信息

BMJ Case Rep. 2013 Jun 3;2013:bcr2013009421. doi: 10.1136/bcr-2013-009421.

DOI:10.1136/bcr-2013-009421
PMID:23737578
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3703010/
Abstract

Simultaneous occurrence of histologically different primary brain tumours is rare, and its preoperative diagnosis is still challenging. The explanations for the simultaneous occurrence of different primary intracranial tumours in the absence of phacomatoses or prior radiation exposure are at present hypothetical, and these tumours could be simply coincidental. Herein, we report a case of a boy presenting with features of raised intracranial pressure and right-sided sensorineural hearing loss. Brain MRI revealed two different neoplastic pathologies at different sites: an intrasellar and suprasellar craniopharyngioma and a right cerebello-pontine angle epidermoid. To the best of our knowledge, this is the first report in literature of a craniopharyngioma coexisting with an epidermoid, in the same individual.

摘要

组织学上不同的原发性脑肿瘤同时出现的情况很少见,其术前诊断仍然具有挑战性。在没有错构瘤或既往放疗史的情况下,不同原发性颅内肿瘤同时出现的原因目前只是推测,这些肿瘤可能仅仅是巧合。在此,我们报告一例男孩,表现为颅内压升高和右侧感音神经性听力丧失。脑部磁共振成像(MRI)显示在不同部位有两种不同的肿瘤病变:鞍内和鞍上颅咽管瘤以及右侧桥小脑角表皮样囊肿。据我们所知,这是文献中首例同一患者中颅咽管瘤与表皮样囊肿共存的报告。

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Craniopharyngioma and epidermoid tumour in same child: a rare association.同一儿童患有颅咽管瘤和表皮样肿瘤:一种罕见的关联。
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Surgical treatment of primary intracranial and extracranial communicating leiomyosarcoma: a case report.原发性颅内与颅外交通性平滑肌肉瘤的外科治疗:一例报告
Front Oncol. 2025 Mar 17;15:1510221. doi: 10.3389/fonc.2025.1510221. eCollection 2025.
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Coexistence of craniopharyngioma and cranial fibrous dysplasia: a case series of clinicopathological study.颅咽管瘤与颅纤维结构不良共存:临床病理研究的病例系列。
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本文引用的文献

1
Multiple primary intracranial tumours; meningioma associated with a glioma; report of a case.多发性原发性颅内肿瘤;脑膜瘤合并胶质瘤;病例报告
J Neuropathol Exp Neurol. 1948 Jan;7(1):81-8. doi: 10.1097/00005072-194801000-00007.
2
Anaplastic astrocytoma and anaplastic oligodendroglioma occurring 6 years after subtotal resection of a central neurocytoma. Case report.中枢神经细胞瘤次全切除术后6年发生间变性星形细胞瘤和间变性少突胶质细胞瘤。病例报告。
J Neurosurg. 2007 Jul;107(1):185-9. doi: 10.3171/JNS-07/07/0185.
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Diagnosis and treatment of pituitary adenomas.垂体腺瘤的诊断与治疗
Minerva Endocrinol. 2004 Dec;29(4):241-75.
4
Oligodendroglioma and juvenile pilocytic astrocytoma presenting as synchronous primary brain tumors. Case report with histological and molecular differentiation of the tumors and review of the literature.少突胶质细胞瘤和青少年毛细胞型星形细胞瘤表现为同步性原发性脑肿瘤。病例报告及肿瘤的组织学和分子鉴别,并文献复习
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[PRIMARY MULTIPLE BRAIN TUMORS].[原发性多发性脑肿瘤]
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Combined oligodendroglioma/pleomorphic xanthoastrocytoma: a probable collision tumor: case report.少突胶质细胞瘤/多形性黄色星形细胞瘤合并:一种可能的碰撞瘤:病例报告
Neurosurgery. 2001 Jun;48(6):1358-61. doi: 10.1097/00006123-200106000-00038.
7
Occurrence of a primary Burkitt-type lymphoma of the central nervous system in an astrocytoma patient. A case report.一名星形细胞瘤患者发生中枢神经系统原发性伯基特型淋巴瘤。病例报告。
Acta Neuropathol. 1981;54(2):165-7. doi: 10.1007/BF00689412.
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Case report. Tandem lesions: chromophobe adenoma and meningioma.
J Comput Assist Tomogr. 1977 Oct;1(4):517-20.