Haugland Trude, Veenstra Marijke, Vatn Morten H, Wahl Astrid K
Clinic for Cancer, Surgery and Transplantation, Oslo University Hospital, Rikshospitalet, 0424 Oslo, Norway ; Department of Nursing Science, University of Oslo, 0318 Oslo, Norway ; Faculty of Medicine, Department of Public Health and Primary Health Care, University of Bergen, 5020 Bergen, Norway.
Nurs Res Pract. 2013;2013:695820. doi: 10.1155/2013/695820. Epub 2013 Apr 23.
The purpose of the study was to evaluate changes in general self-efficacy, health related quality of life (HRQoL), and stress among patients with neuroendocrine tumors (NET) following a multidisciplinary educational intervention. Forty-one patients were enrolled in this exploratory pilot study. A total of 37 patients completed the full 26-week intervention based on the principles of self-efficacy. General self-efficacy was measured by the General Self-Efficacy Scale, HRQoL was measured with the SF-36, and stress was measured with the Impact of Event Scale. Mixed effect models were used to evaluate changes in general self-efficacy, mental and physical components of HRQoL, and stress adjusting for demographic and clinical variables. Results showed significant improvements in patients' general self-efficacy (β = 0.71; P < 0.05), physical component scores of HRQoL (β = 3.09; P < 0.01), and stress (β = -2.10, P = 0.008). Findings suggest that patients with NET have the capacity to improve their ability to cope with their disease, problem-solve, improve their physical status, and reduce their stress following an educational intervention based on the principles of self-efficacy. These preliminary data provide a basis for future randomized controlled trials to test interventions to improve HRQoL for patients with NET.
本研究的目的是评估多学科教育干预后神经内分泌肿瘤（NET）患者的一般自我效能感、健康相关生活质量（HRQoL）和压力的变化。41名患者参与了这项探索性试点研究。共有37名患者基于自我效能感原则完成了为期26周的完整干预。一般自我效能感通过一般自我效能量表进行测量，HRQoL通过SF-36进行测量，压力通过事件影响量表进行测量。混合效应模型用于评估一般自我效能感、HRQoL的心理和生理成分以及调整人口统计学和临床变量后的压力变化。结果显示，患者的一般自我效能感（β = 0.71；P < 0.05）、HRQoL的生理成分得分（β = 3.09；P < 0.01）和压力（β = -2.10，P = 0.008）有显著改善。研究结果表明，NET患者有能力在基于自我效能感原则的教育干预后提高应对疾病的能力、解决问题的能力、改善身体状况并减轻压力。这些初步数据为未来的随机对照试验提供了基础，以测试改善NET患者HRQoL的干预措施。
