Kumar Vijay, Kumar Adarsh, Varshney A C
Department of Veterinary Surgery and Radiology DGCN, College of Veterinary and Animal Sciences, CSK HP Agricultural University, Himachal Pradesh, Palampur 176062, India.
ISRN Vet Sci. 2011 Dec 25;2011:901713. doi: 10.5402/2011/901713. Print 2011.
The present study comprises of 10 dogs of either sex with primary indication of azotaemia. All the dogs were subjected to detailed clinical, haematobiochemical, urinalysis, and microbiological examination along with radiographical and ultrasonographical examination. Based on the ultrasonographic structural abnormalities, the different renal affections associated with CRF in majority of dogs were diagnosed. The different affections included "end-stage" kidneys (n = 4), hydronephrosis (n = 1), renomegaly (n = 1), nephritis (n = 1), nephrolithiasis (n = 1), nephrocalcinosis (n = 1), and renal cyst (n = 1). The significant ultrasonographic features in these affections included small kidneys with loss of corticomedullary demarcation ("end-stage" kidneys); increased cortical echogenicity (nephritis); dilation of the renal pelvis, separation of the central renal sinus with anechoic space, atrophy of renal medulla, (hydronephrosis); enlarged kidneys with increased overall echogenicity of renal cortex (renomegaly and associated nephritis); hyperechoic-mineralized structure with shadowing (nephrolithiasis); diffuse, small, multiple hyperechoic structures in the renal parenchyma with distal acoustic shadowing (nephrocalcinosis); small spherical intercortical anechoic structures fluid (renal cysts). In the present study, ultrasound proved to be a quick, convenient, and sensitive modality in detecting alterations in renal size and parenchymal architecture. All the dogs so diagnosed with CRF were rendered conservative medical treatment to control clinical signs of uraemia; maintain adequate fluid, electrolyte, and acid/base balance; provide adequate nutrition; minimize progression of renal failure.
本研究包括10只患有氮血症主要指征的雌雄犬。所有犬均接受了详细的临床、血液生化、尿液分析和微生物学检查,以及放射学和超声检查。根据超声结构异常,诊断出大多数犬与慢性肾衰竭相关的不同肾脏病变。不同的病变包括“终末期”肾脏(n = 4)、肾积水(n = 1)、肾肿大(n = 1)、肾炎(n = 1)、肾结石(n = 1)、肾钙质沉着症(n = 1)和肾囊肿(n = 1)。这些病变的显著超声特征包括皮质髓质分界消失的小肾脏(“终末期”肾脏);皮质回声增强(肾炎);肾盂扩张、肾窦中央分离伴无回声区、肾髓质萎缩(肾积水);肾脏增大,肾皮质整体回声增强(肾肿大及相关肾炎);伴有声影的高回声矿化结构(肾结石);肾实质内弥漫性、小的、多个高回声结构伴远端声影(肾钙质沉着症);肾皮质内小球形无回声液性结构(肾囊肿)。在本研究中,超声被证明是一种快速、便捷且敏感的检测肾脏大小和实质结构改变的方法。所有诊断为慢性肾衰竭的犬均接受了保守药物治疗,以控制尿毒症的临床症状;维持足够的液体、电解质和酸碱平衡;提供足够的营养;尽量减少肾衰竭的进展。